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15721

Sigma-Aldrich

Polydatin

≥95% (HPLC)

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Synonym(s):
Piceid, Reservatrol-3-β-mono-D-glucoside, Resveratrol 3-O-β-D-glucopyranoside
Empirical Formula (Hill Notation):
C20H22O8
CAS Number:
Molecular Weight:
390.38
Beilstein:
54837
PubChem Substance ID:
NACRES:
NA.25

Assay

≥95% (HPLC)

form

powder

optical activity

[α]1/D -66.0±2.0° in ethanol

composition

carbon, 60.5-62.5%

storage temp.

2-8°C

SMILES string

OCC1O[C@@H](Oc2cc(O)cc(\C=C\c3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16?,17-,18+,19-,20-/m1/s1

InChI key

HSTZMXCBWJGKHG-AEGFYQLOSA-N

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This Item
SMB0094810050A6005
Polydatin ≥95% (HPLC)

Sigma-Aldrich

15721

Polydatin

-
Amygdalin BioXtra, ≥97.0% (HPLC)

Sigma-Aldrich

10050

Amygdalin

Premium Grade
Amygdalin from apricot kernels, ≥99%

Sigma-Aldrich

A6005

Amygdalin

-
form

powder

form

solid

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

room temp

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

300

optical activity

[α]1/D -66.0±2.0° in ethanol

optical activity

-

optical activity

[α]20/D −39±2°, c = 2% in H2O

optical activity

-

composition

carbon, 60.5-62.5%

composition

-

composition

-

composition

-

Application

Polydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities. Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibits therapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the direct protection of neurons.

Biochem/physiol Actions

Stilbene found in medicinal herbs. Antioxidant, anti-inflammatory and neuroprotective.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hong Zhang et al.
PloS one, 7(9), e46574-e46574 (2012-10-03)
Polydatin is one of main compounds in Polygonum cuspidatum, a plant with both medicinal and nutritional value. The possible hepatoprotective effects of polydatin on acute liver injury mice induced by carbon tetrachloride (CCl(4)) and the mechanisms involved were investigated. Intraperitoneal
Giampietro Ravagnan et al.
Inflammation, 36(1), 26-34 (2012-09-08)
It is well known that human keratinocytes produce the anti-microbial peptide β-defensin 2. Its production is enhanced by pathogenic microorganisms or other environmental stressors. In this study, we evaluated the effect of resveratrol, a polyphenol found in several dietary source
Maria Rotches-Ribalta et al.
Pharmacological research, 66(5), 375-382 (2012-08-22)
A pharmacokinetic study of the metabolic profile of resveratrol has been performed in healthy men after moderate red wine (RW) consumption. The bioavailability of resveratrol is highly influenced by several factors such as the food matrix and, therefore, this study
Xingmin Wang et al.
Expert opinion on investigational drugs, 22(2), 169-179 (2012-12-18)
The aim of the study was find out whether neuronal mitochondrial injury does take place in severe shock and to explore effective therapy for severe shock. Rats were divided in the following group: sham, shock + normal saline (NS), shock
Jianxin Deng et al.
Journal of molecular and cellular cardiology, 53(5), 646-656 (2012-08-28)
Polydatin (PD), a resveratrol glucoside, has recently been suggested to have cardioprotective effects against heart diseases, including ischemia-reperfusion injury and pressure-overload induced ventricular remodeling. However, the mechanisms are poorly understood. This study aims to investigate the direct effects of PD

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