추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 20 mg/mL, clear
저장 온도
2-8°C
SMILES string
OC1=CC2=C(C=C(C3=CC=C(C(O)=O)C=C3)C=C2)C=C1C4(C[C@H](C5)C6)C[C@H]6C[C@H]5C4
InChI
1S/C27H26O3/c28-25-12-22-6-5-21(19-1-3-20(4-2-19)26(29)30)10-23(22)11-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChI key
VCQGNUWOMLYNNG-UHFFFAOYSA-N
생화학적/생리학적 작용
CD1530 is a potent and selective agonist of retinoic acid receptor RARγ with Kd values of 150, 1,500, and 2,750 nM for RARγ, RARβ, and RARα receptors, respectively. In various studies, CD1530 has been shown to preserve human tendon stem cell characteristics, promote repair of injured skeletal muscle, and in combination with bexarotene to inhibit oral carcinogenesis.
CD1530 is a potent and selective agonist of retinoic acid receptor RARγ.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Agnese Di Rocco et al.
The American journal of pathology, 185(9), 2495-2504 (2015-07-25)
Retinoic acid signaling regulates several biological events, including myogenesis. We previously found that retinoic acid receptor γ (RARγ) agonist blocks heterotopic ossification, a pathological bone formation that mostly occurs in the skeletal muscle. Interestingly, RARγ agonist also weakened deterioration of
Steven E Trasino et al.
Journal of molecular medicine (Berlin, Germany), 94(10), 1143-1151 (2016-06-09)
Hepatic stellate cells (HSCs) are an important cellular target for the development of novel pharmacological therapies to prevent and treat nonalcoholic fatty liver diseases (NAFLD). Using a high fat diet (HFD) model of NAFLD, we sought to determine if synthetic
Stuart Webb et al.
Stem cell research & therapy, 7, 45-45 (2016-03-24)
Previous studies have reported that adult mesenchymal stem cells (MSCs) tend to gradually lose their stem cell characteristics in vitro when placed outside their niche environment. They subsequently undergo spontaneous differentiation towards mesenchymal lineages after only a few passages. We
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