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CA9

carbonic anhydrase IX

Synonyms:
CAIX, MN
Species:
UniProtKB ID:
Gene ID:
  • Human(768) Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jul 2008]
  • Zebrafish(566612) carbonic anhydrase IX
  • chicken(770004) carbonic anhydrase IX
  • dog(611933) carbonic anhydrase IX
  • domestic cat(101092802) carbonic anhydrase IX
  • Horse(100055579) carbonic anhydrase IX
  • cow(511923) carbonic anhydrase IX
  • sheep(101115682) carbonic anhydrase IX
  • domestic guinea pig(100729644) carbonic anhydrase IX
  • naked mole-rat(101722784) carbonic anhydrase IX

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Human Carbonic Anhydrase IX ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Carbonic Anhydrase 9 (CA9/G250) antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-CA9 Antibody, clone 1B6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-CA9 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-CA9 Antibody, clone 2D3, ascites fluid, clone 2D3, from mouse,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

western blot
Monoclonal Anti-CA9 antibody produced in mouse, clone 2D3, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Methyl 2-(aminosulfonyl)benzoate, 98%,
Species
human
4-Sulfamoylbenzoic acid, 97%,
Species
human
4-Amino-6-chloro-1,3-benzenedisulfonamide, 98%,
Species
human
2-Aminobenzenesulfonamide, 98%,
Species
human, mouse
4-Aminomethylbenzenesulfonamide hydrochloride, analytical standard, ≥95%,
Species
human, mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CA9,
Species
human