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S9251

Sigma-Aldrich

Sulfanilamide

≥98%

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Synonym(s):
4-aminobenzenesulfonamide, p-Aminobenzenesulfonamide
Linear Formula:
H2NC6H4SO2NH2
CAS Number:
Molecular Weight:
172.20
Beilstein:
511852
EC Number:
MDL number:
eCl@ss:
39093202
PubChem Substance ID:
NACRES:
NA.76

Quality Level

Assay

≥98%

form

powder or crystals

color

white to off-white

mp

164-166 °C (lit.)

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

DNA synthesis | interferes
enzyme | inhibits

SMILES string

Nc1ccc(cc1)S(N)(=O)=O

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

Inchi Key

FDDDEECHVMSUSB-UHFFFAOYSA-N

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This Item
33626468741632004
Sulfanilamide ≥98%

Sigma-Aldrich

S9251

Sulfanilamide

Sulfanilamide puriss. p.a., ≥99% (calc. to the dried substance)

Sigma-Aldrich

33626

Sulfanilamide

Sulfanilamide VETRANAL®, analytical standard

Supelco

46874

Sulfanilamide

Sulfanilamide United States Pharmacopeia (USP) Reference Standard

USP

1632004

Sulfanilamide

form

powder or crystals

form

solid

form

-

form

-

color

white to off-white

color

white to faint beige

color

-

color

-

mp

164-166 °C (lit.)

mp

163-166 °C, 164-166 °C (lit.)

mp

164-166 °C (lit.)

mp

164-166 °C (lit.)

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

antibiotic activity spectrum

-

mode of action

DNA synthesis | interferes, enzyme | inhibits

mode of action

DNA synthesis | interferes, enzyme | inhibits

mode of action

DNA synthesis | interferes, enzyme | inhibits

mode of action

-

General description

Chemical structure: sulfonamide

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: A competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A beta-carbonic anhydrase (CA, EC 4.2.1.1) from the bacterial pathogen Brucella suis, bsCA 1, has been cloned, purified characterized kinetically and for inhibition with a series of water soluble glycosylated sulfanilamides. bsCA 1 has appreciable activity as catalyst for the
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Coumarins constitute a general and totally new class of inhibitors of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), binding at the entrance of the active site cavity. We report here that the coumarin-binding site in CAs may interact with
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