MilliporeSigma

GABRB1

gamma-aminobutyric acid (GABA) A receptor, beta 1

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2560) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
  • Mouse(14400) gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
  • Rat(25450) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • Zebrafish(100331377) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • sheep(101122358) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • naked mole-rat(101717539) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic guinea pig(100719515) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic cat(101097640) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • dog(100687745) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • cow(282239) gamma-aminobutyric acid (GABA) A receptor, beta 1

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Small Molecule - Agonist

Product Number
Description
Species
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
Isoguvacine hydrochloride, solid,
Species
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Zaleplon, United States Pharmacopeia (USP) Reference Standard,
Species
human
Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
Species
human
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Picrotoxin, powder,
Species
human
Pregnenolone sulfate sodium salt, ,
Species
human
SR-95531, ≥98% (HPLC), powder,
Species
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Species
human
trans-Dehydroandrosterone, ≥99%,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABRB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-GABRB1 (Ab-434) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-GABA A Receptor β 1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-GABA A Receptor beta 1 (GABRB1) Antibody, clone 1Q3A9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-phospho-GABA-RB (pSer434) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
(±)-Vigabatrin, ,
Species
human
2,6-Diisopropylphenol, 97%,
Species
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Etomidate, >98% (HPLC), powder,
Species
human
Flumazenil, >99% (HPLC), solid,
Species
rat, human
Carbamazepine, powder,
Species
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gabrb1,
Species
mouse
MISSION® esiRNA, targeting human GABRB1,
Species
human