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Z-004

Supelco

Zaleplon solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C17H15N5O
CAS Number:
151319-34-5
Molecular Weight:
305.33
EC Number:
200-659-6
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CCN(C(C)=O)c1cccc(c1)-c2ccnc3c(cnn23)C#N

InChI

1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3

InChI key

HUNXMJYCHXQEGX-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRB1(2560) , GABRG2(2566)

Related Categories

General description

Zaleplon is a nonbenzodiazepine “Z-drug” prescribed under the trade names Sonata® or Starnoc for the treatment of insomnia. Zaleplon is often abused illicitly for its mind-altering effects. This Certified Spiking Solution® is applicable to use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis.

Application


  • Controlled pore glass beads: Controlled pore glass can be employed for sustainable functionalized metal-organic frameworks for CO2 separation, showcasing the material′s effectiveness in environmental applications due to its high BET surface area which enhances gas adsorption properties (Babar et al., 2021).

  • Porous glass for protein adsorption: Mesoporous nano-bioglass for controlled drug release, highlights the application of controlled pore glass with high surface areas in pharmaceutical formulations to enhance the delivery and efficacy of therapeutic agents (Shoaib et al., 2017).

  • Surface characterization materials: It can be employed for the contact angle hysteresis of materials with controlled pore structures, to understand the wetting properties of high surface area materials like controlled pore glass, which is critical in various industrial and biomedical applications (Salmas and Androutsopoulos, 2001).


Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Sonata is a registered trademark of King Pharmaceuticals Research and Development, Inc.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yu-Shu Huang et al.
Chang Gung medical journal, 34(1), 50-56 (2011-03-12)
Benzodiazepines cause a high proportion of adverse effects while non-benzodiazepine compounds have demonstrated high efficacy and less adverse effects in patients with insomnia. The objective of this study was to compare the effectiveness and safety of non-BZ zaleplon and zolpidem
A case of zaleplon-induced amnestic sleep-related eating disorder.
Shanna M Molina et al.
The Journal of clinical psychiatry, 71(2), 210-211 (2010-03-03)
Ane Birgitte Telén Andersen et al.
Pharmacoepidemiology and drug safety, 20(4), 378-385 (2011-01-25)
To estimate the degree of long-term use of zopiclone, zolpidem and zaleplon among Danes aged 65 and older and the association with sociodemographic factors and use of other drugs. Danish register-based study of 5000 men and 5000 women aged 65
Insomnia: evidence-based approaches to assessment and management.
Kevin Morgan et al.
Clinical medicine (London, England), 11(3), 278-281 (2011-09-10)
Karthik Y Janga et al.
Journal of microencapsulation, 30(2), 161-172 (2012-08-17)
Self-nanoemulsifying drug delivery systems (SNEDDSs) offer potential as suitable carriers for improved oral delivery of poorly soluble and low bioavailable drugs. To derive self-nanoemulsifying powders (SNEPs), the optimized Z-SNEDDS formulation was adsorbed onto different carriers and based on micromeritics the
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