MilliporeSigma

GRIA3

glutamate receptor, ionotropic, AMPA 3

Synonyms:
GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94
Species:
UniProtKB ID:
Gene ID:
  • Human(2892) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
  • Mouse(53623) glutamate receptor, ionotropic, AMPA3 (alpha 3)
  • Rat(29628) glutamate receptor, ionotropic, AMPA 3
  • chicken(396138) glutamate receptor, ionotropic, AMPA 3
  • sheep(443273) glutamate receptor, ionotropic, AMPA 3
  • cow(534626) glutamate receptor, ionotrophic, AMPA 3
  • dog(492110) glutamate receptor, ionotropic, AMPA 3
  • Horse(100055136) glutamate receptor, ionotropic, AMPA 3
  • naked mole-rat(101713289) glutamate receptor, ionotropic, AMPA 3
  • domestic cat(101089925) glutamate receptor, ionotropic, AMPA 3
  • Domestic Rabbit(100341980) glutamate receptor, ionotropic, AMPA 3

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Small Molecule - Agonist

Product Number
Description
Species
2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide, ≥98% (HPLC), solid,
Species
human
Cyclothiazide, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat
(S)-AMPA, ≥98%,
Species
mouse, human, rat
(Aminomethyl)phosphonic acid, 99%,
Species
rat, human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
CX546, ≥98% (HPLC), solid,
Species
human
Piracetam, ,
Species
human, rat
Cyclothiazide, ,
Species
human, rat
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
GYKI 52466 hydrochloride, solid,
Species
human
Piracetam, ,
Species
human, rat
CNQX disodium salt hydrate, ≥98% (HPLC), solid,
Species
human
NBQX disodium salt hydrate, ≥98% (HPLC),
Species
human
(±)-AMPA, solid,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GRIA3 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-GRIA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Glutamate Receptor 3 Antibody, clone 3B3, clone 3B3, Chemicon®, from mouse,
Species Reactivity
human, monkey, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-GRIA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Cyclothiazide, ,
Species
human, rat
Kynurenic acid, ≥98%,
Species
rat, human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Cyclothiazide, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GRIA3,
Species
human
MISSION® esiRNA, targeting mouse Gria3,
Species
mouse