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MilliporeSigma

1.07427

SAFC

Propyl 4-hydroxybenzoate

EMPROVE® EXPERT, Ph. Eur., BP, JP, NF

Pharma Manufacturing

Synonym(s):

Propyl 4-hydroxybenzoate, Propylparaben

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About This Item

Empirical Formula (Hill Notation):
C10H12O3
CAS Number:
Molecular Weight:
180.20
MDL number:
UNSPSC Code:
12352108
EC Index Number:
202-307-7

agency

BP
JP
NF
Ph. Eur.

Quality Level

vapor pressure

0.67 hPa ( 122 °C)

product line

EMPROVE® EXPERT

form

solid

autoignition temp.

>600 °C

potency

>5000 mg/kg LD50, oral (Rat)

technique(s)

API processing | cocrystal formation: suitable

pH

6-7 (20 °C in H2O, saturated solution)

mp

96-98 °C

transition temp

flash point 180 °C

solubility

0.4 g/L

density

1.063 g/cm3 at 102 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3

InChI key

QELSKZZBTMNZEB-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

hcodes

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

356.0 °F

flash_point_c

180 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

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