Solubility is an important aspect of solid and liquid drug formulation. Active pharmaceutical ingredient (API) solubility is critical for the success of the final dosage form and is necessary for the API’s absorption in the body and its therapeutic effect. As more and more APIs are poorly soluble, it’s crucial to take steps to enhance solubility either through API processing or formulation.
But why start optimizing API solubility during the late stage of formulation when you can truly enhance your API’s performance from the beginning?
Choose API processing to:
There are many techniques available for API processing based on your specific API’s characteristics and needs.
We provide a range of high-quality chemicals which target different API processing techniques. This way, you can focus on commercialization instead of on solubilization.
Explore our offering for:
Especially for salt and co-crystal formation, raw material quality is critical as the counterion and co-former are considered parts of the API by regulatory agencies. Whichever of these API processing methods you decide to use, we provide you with high-quality API processing chemicals which are part of the Emprove® Program. This provides 24/7 access to comprehensive documentation to support your management of regulatory- and quality-associated risks.
Our offering and service goes well beyond just supplying products for API processing. We offer easy access to an extensive portfolio of high-quality raw materials solutions that are easy to use, ensure product and patient safety, and meet your drug development and manufacturing needs. These products are designed to address pharmaceutical processes and manufacturing across all dosage forms.
Instead of addressing API solubility during formulation, tackle it early during development. Read about the various methods for API processing.
Find details on why salt and cocrystal formation are important parts of the toolbox for drug development for challenging APIs.
Browse the flyer showcasing the different API processing techniques along with suitable products
Explore products and services for each step of your pharmaceutical manufacturing process.
About benefits and challenges of salt and cocrystal formation, and selecting salts and co-formers for complex APIs.
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