1.00563

ortho-Phosphoric acid

85%, EMPROVE^® ESSENTIAL, Ph. Eur., BP, JPE, NF, E 338

• Synonym(s): Phosphoric acid, o-Phosphoric acid, Orthophosphoric acid, Orthophosphoric acid
• Linear Formula: H₃PO₄
• CAS Number: 7664-38-2
• Molecular Weight: 98.00
• Beilstein: 1921286
• MDL number: MFCD00011340
• E Number: E338

Properties

• Agency: BP; JPE; NF; Ph. Eur.
• Quality Level: 500
• vapor density: 3.4 (vs air)
• vapor pressure: 2.2 mmHg ( 20 °C); 5 mmHg ( 25 °C)
• product line: EMPROVE^® ESSENTIAL
• form: liquid
• concentration: 85%
• technique(s): API processing | salt formation: suitable
• pH: <0.5 (20 °C, 100 g/L in H₂O)
• kinematic viscosity: 30.5 cSt(20 °C)
• bp: 158 °C (lit.)
• mp: ~40 °C (lit.)
• density: 1.685 g/mL at 25 °C (lit.)
• application(s): liquid formulation; ophthalmics; pharma/biopharma processes; pharmaceutical; semi-solid formulation
• storage temp.: 2-30°C
• SMILES string: OP(O)(O)=O
• InChI: 1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
• InChI key: NBIIXXVUZAFLBC-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Phosphoric acid can be used as acidifying agent in a variety of pharmaceutical formulations and processes.

Other Notes

Concentrated phosphoric acid is approx. 85% H₃PO₄ (aqueous).

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H290 - H302 - H314
• Precautionary Statements: P234 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Storage Class Code: 8B - Non-combustible, corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): does not flash
• Flash Point(C): does not flash