MilliporeSigma

1.00013

SAFC

Acetone

EMPROVE® ESSENTIAL, Ph. Eur., BP, JPE, NF

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Synonym(s):
Dimethyl ketone, Propanone, 2-Propanone
Linear Formula:
CH3COCH3
CAS Number:
Molecular Weight:
58.08
Beilstein:
635680
MDL number:
EC Index Number:
200-662-2

Agency

BP
JPE
NF
Ph. Eur.

Quality Level

vapor density

2 (vs air)

vapor pressure

184 mmHg ( 20 °C)

description

EMPROVE® ESSENTIAL Ph Eur,BP,JPE,NF

product line

EMPROVE® ESSENTIAL

Assay

≥99% (GC)

form

liquid

autoignition temp.

465 °C (DIN 51794)

expl. lim.

13.2 %

technique(s)

API processing | polymorph screening: suitable

refractive index

n20/D 1.359 (lit.)

pH

5-6 (20 °C, 395 g/L in H2O)

capacity

1000  g/kg water absorbing capacity

bp

56 °C/760 mmHg (lit.)

mp

−94 °C (lit.)

transition temp

flash point <-20 °C

density

0.791 g/mL at 25 °C (lit.)

application(s)

liquid formulation
pharma/biopharma processes
pharmaceutical

format

neat

storage temp.

2-30°C

SMILES string

CC(C)=O

InChI

1S/C3H6O/c1-3(2)4/h1-2H3

InChI key

CSCPPACGZOOCGX-UHFFFAOYSA-N

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1 of 4

This Item
1.008641.062811.28202
Acetone EMPROVE&#174; ESSENTIAL, Ph. Eur., BP, JPE, NF

SAFC

1.00013

Acetone

Ethyl acetate EMPROVE&#174; ESSENTIAL, Ph. Eur., BP, NF

SAFC

1.00864

Ethyl acetate

Sodium acetate anhydrous, EMPROVE&#174; ESSENTIAL, USP, FCC, E 262

SAFC

1.06281

Sodium acetate

Sodium acetate anhydrous EMPROVE&#174; EXPERT, ChP, USP

SAFC

1.28202

Sodium acetate anhydrous

vapor pressure

184 mmHg ( 20 °C)

vapor pressure

73 mmHg ( 20 °C)

vapor pressure

-

vapor pressure

-

assay

≥99% (GC)

assay

98.0-102.0% (GC)

assay

-

assay

-

form

liquid

form

liquid

form

solid

form

solid

autoignition temp.

465 °C (DIN 51794)

autoignition temp.

801 °F

autoignition temp.

1112 °F, 607 °C

autoignition temp.

1112 °F

expl. lim.

13.2 %

expl. lim.

2.2-11.5 %, 38 °F

expl. lim.

-

expl. lim.

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Acetone is used as solvent in a variety of pharmaceutical production processes, e. g. tablet coating, granulation, and microsphere production. It is also applied as solvent or co-solvent in topical formulations.
Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

1.4 °F - closed cup

Flash Point(C)

-17.0 °C - closed cup


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