MilliporeSigma

1.00056

SAFC

Acetic acid

(glacial) 100%, EMPROVE® EXPERT, Ph. Eur., BP, JP, USP, E 260

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Synonym(s):
Acetic acid, Ethanoic acid, Glacial acetic acid
Linear Formula:
CH3CO2H
CAS Number:
Molecular Weight:
60.05
Beilstein:
506007
MDL number:
E Number:
E260
EC Index Number:
200-580-7

Agency

BP
JP
Ph. Eur.
USP

Quality Level

vapor density

2.07 (vs air)

vapor pressure

15.4 hPa ( 20 °C)

product line

EMPROVE® EXPERT

Assay

≥99.8-100.5% (alkalimetric)

form

liquid

autoignition temp.

485 °C
800 °F

expl. lim.

16 %, 92 °F
4 %, 59 °F

concentration

100%

technique(s)

API processing | polymorph screening: suitable

refractive index

n20/D 1.371 (lit.)

pH

2.5 (20 °C, 50 g/L in H2O)

kinematic viscosity

1.17 cSt(20 °C)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

transition temp

flash point 39 °C

solubility

soluble 602.9 g/L

density

1.049 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.0002%
sulfate (SO42-): ≤0.0005%

cation traces

Al: ≤0.00005%
As: ≤0.00010%
Cu: ≤0.0005%
Fe: ≤0.0005%
Hg: ≤0.00010%
Pb: ≤0.00005%
Zn: ≤0.0005%
heavy metals (as Pb): ≤0.0005%

application(s)

liquid formulation
pharmaceutical
semi-solid formulation

storage temp.

15-25°C

SMILES string

CC(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

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1 of 4

This Item
1.000581.3703433209
Acetic acid (glacial) 100%, EMPROVE® EXPERT, Ph. Eur., BP, JP, USP, E 260

SAFC

1.00056

Acetic acid

-
Acetic acid 96%, EMPROVE® ESSENTIAL

SAFC

1.00058

Acetic acid

-
Acetic acid 60%, EMPROVE® EXPERT

SAFC

1.37034

Acetic acid

-
Acetic acid glacial, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.8%

Sigma-Aldrich

33209

Acetic acid

Essential Grade
vapor density

2.07 (vs air)

vapor density

2.07 (vs air)

vapor density

2.07 (vs air)

vapor density

2.07 (vs air)

vapor pressure

15.4 hPa ( 20 °C)

vapor pressure

15.2 hPa ( 20 °C)

vapor pressure

-

vapor pressure

-

assay

≥99.8-100.5% (alkalimetric)

assay

-

assay

-

assay

≥99.8%

form

liquid

form

liquid

form

-

form

liquid

concentration

100%

concentration

96%

concentration

-

concentration

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Acetic acid can be used as acidifying agent and buffer component in a variety of pharmaceutical formulations and production processes, including e.g. plasma fractionation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

102.2 °F

Flash Point(C)

39 °C


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