MilliporeSigma

8.17072

SAFC

TWEEN® 20 (Polysorbate)

EMPROVE® ESSENTIAL, Ph. Eur., JPE, NF

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Synonym(s):
TWEEN® 20, Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate
CAS Number:
MDL number:
EC Index Number:
500-018-3

Agency

JPE
NF
Ph. Eur.

Quality Level

vapor pressure

<1.4 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

form

viscous liquid

mol wt

~1228

technique(s)

API processing | nano-milling: suitable

refractive index

n20/D 1.468 (lit.)

pH

6-8 (20 °C, 50 g/L in H2O)

transition temp

flash point 275 °C

density

1.095 g/mL at 25 °C (lit.)

application(s)

liquid formulation
ophthalmics
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

storage temp.

15-25°C

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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This Item
1.371728.22184655205
TWEEN&#174; 20 (Polysorbate) EMPROVE&#174; ESSENTIAL, Ph. Eur., JPE, NF

SAFC

8.17072

TWEEN® 20 (Polysorbate)

Polysorbate 20 high purity, EMPROVE&#174; EXPERT, Ph. Eur., ChP, JPE, NF

SAFC

1.37172

Polysorbate 20

TWEEN&#174; 20 for synthesis

Sigma-Aldrich

8.22184

TWEEN® 20

TWEEN&#174; 20 Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins.

Millipore

655205

TWEEN® 20

form

viscous liquid

form

liquid

form

liquid

form

liquid

mol wt

~1228

mol wt

1228 g/mol

mol wt

~1228

mol wt

~1228

technique(s)

API processing | nano-milling: suitable

technique(s)

-

technique(s)

-

technique(s)

-

transition temp

flash point 275 °C

transition temp

-

transition temp

flash point 275 °C

transition temp

-

density

1.095 g/mL at 25 °C (lit.)

density

1.1 g/cm3 at 25 °C

density

1.095 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polysorbate 20 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent.
Non-ionic detergent

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

527.0 °F - Pensky-Martens closed cup

Flash Point(C)

275 °C - Pensky-Martens closed cup


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