MilliporeSigma

1.41464

SAFC

Parteck® MXP (Polyvinyl alcohol 4-88)

EMPROVE® ESSENTIAL, Ph. Eur., ChP, JPE, USP

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Synonym(s):
Parteck® Polyvinyl alcohol, PVA, PVOH
Linear Formula:
(C2H4O)n
CAS Number:
MDL number:

Agency

ChP
JPE
Ph. Eur.
USP

Quality Level

product line

EMPROVE® ESSENTIAL

form

fine powder

particle size

≤200 μm (d95)

mp

160-240 °C

application(s)

controlled release
pharmaceutical
solid formulation
solubility enhancement

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

Inchi Key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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1 of 4

This Item
1.414391.415171.03668
Parteck® M DPI EMPROVE® EXPERT, Ph. Eur., BP, JP, USP, E 421

SAFC

1.03668

Parteck® M DPI

form

fine powder

form

fine powder

form

fine powder

form

fine powder

mp

160-240 °C

mp

160-240 °C

mp

160-240 °C

mp

164-169 °C

application(s)

controlled release
pharmaceutical
solid formulation
solubility enhancement

application(s)

controlled release
pharmaceutical
solid formulation

application(s)

pharmaceutical
solid formulation

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

2-25°C

Quality Level

500

Quality Level

500

Quality Level

500

Quality Level

500

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck® MXP excipient is a polyvinyl alcohol-based excipient specifically designed for hot-melt extrusion to increase the solubility of poorly water soluble APIs via stabilization of the amorphous solid state. Parteck® MXP enables stable and high drug loads and can be used for a broad range of poorly water soluble APIs and a variety of final dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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