MilliporeSigma

1.41544

SAFC

Parteck® MXP (Polyvinyl alcohol 3-82)

EMPROVE® ESSENTIAL, Ph. Eur.

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Synonym(s):
Parteck® Polyvinyl alcohol, PVA, Polyvinyl alcohol
Linear Formula:
(C2H4O)n
CAS Number:
MDL number:

Agency

Ph. Eur.

Quality Level

product line

EMPROVE® ESSENTIAL

form

powder

application(s)

pharmaceutical
solid formulation
solubility enhancement

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

General description

With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interac­tions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologi­cally relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.

Application

Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

No data available

Flash Point(C)

No data available


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Articles

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

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