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A5000

Sigma-Aldrich

Acetaminophen

meets USP testing specifications, 98.0-102.0%, powder

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Synonym(s):
4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol
Linear Formula:
CH3CONHC6H4OH
CAS Number:
Molecular Weight:
151.16
Beilstein/REAXYS Number:
2208089
MDL number:
PubChem Substance ID:
NACRES:
NA.25

agency

USP/NF
meets USP testing specifications

Quality Level

assay

98.0-102.0%

form

powder

mp

168-172 °C (lit.)

solubility

DMSO: 5 M
ethanol: 50 mg/mL
H2O: very slightly soluble

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Gene Information

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1 of 4

This Item
A70851003009PHR1005
vibrant-m

A5000

Acetaminophen

-
vibrant-m

A7085

Acetaminophen

Premium Grade
vibrant-m

1003009

Acetaminophen

-
vibrant-m

PHR1005

Acetaminophen

-
form

powder

form

powder

form

-

form

-

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

300

solubility

DMSO: 5 M, H2O: very slightly soluble, ethanol: 50 mg/mL

solubility

ethanol: 0.5 M, clear, colorless

solubility

-

solubility

-

agency

USP/NF

agency

-

agency

-

agency

traceable to BP 371, traceable to Ph. Eur. P030000, traceable to USP 1003009

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

Application

Analgesic.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

364.3 °F - Pensky-Martens closed cup

flash_point_c

184.6 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Customers Also Viewed

Slide 1 of 7

1 of 7

Mohammad A Rahman et al.
Scientific reports, 9(1), 6571-6571 (2019-04-27)
Cellular CYP2E1 is well-known to mediate alcohol- (ALC) and acetaminophen- (APAP) induced toxicity in hepatic and extra-hepatic cells. Although exosomes have been gaining importance in understanding mechanism of intra- and inter-cellular communication, the functional role of drug metabolizing cytochrome P450
S M de Morais et al.
Gastroenterology, 102(2), 577-586 (1992-02-01)
Gilbert's syndrome occurs in 5%-7% of the human population and is caused by an inherited deficiency in the glucuronidation of endogenous bilirubin, resulting in its accumulation and jaundice. The authors of the present study have previously shown that rats with
Karel Allegaert et al.
Archives of disease in childhood, 98(6), 462-466 (2013-04-23)
There remains a need for alternative medical treatments for patent ductus arteriosus (PDA) closure in extreme preterm neonates because of therapeutic failure and adverse effects associated with non-selective cyclo-oxygenase inhibitors. Reports of an association between paracetamol exposure and PDA closure
Garry G Graham et al.
Drug safety, 28(3), 227-240 (2005-03-01)
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported
Garry G Graham et al.
Inflammopharmacology, 21(3), 201-232 (2013-05-31)
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors. Paracetamol is, on average, a weaker analgesic than NSAIDs or COX-2 selective

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