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95904

Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 4,000

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Synonym(s):
PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

product line

BioUltra

form

powder

mol wt

Mr 3500-4500

impurities

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

58-61 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: ≤0.10
λ: 280 nm Amax: ≤0.04

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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1 of 4

This Item
895108128081242
vibrant-m

95904

Poly(ethylene glycol)

Premium Grade
vibrant-m

89510

Poly(ethylene glycol)

Premium Grade
vibrant-m

81280

Poly(ethylene glycol)

-
vibrant-m

81242

Poly(ethylene glycol)

-
Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

mp

58-61 °C

mp

61-64 °C

mp

62-65 °C

mp

-

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

impurities

-

impurities

-

mol wt

Mr 3500-4500

mol wt

Mr 7000-9000

mol wt

8500-11500

mol wt

3500-4500

cation traces

Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤200 mg/kg, Mg: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Sr: ≤5 mg/kg, As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Mn: ≤5 mg/kg, Pb: ≤5 mg/kg, Bi: ≤5 mg/kg, Li: ≤5 mg/kg, Zn: ≤5 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

cation traces

-

cation traces

-

General description

Poly(ethylene glycol) (PEG) is a polymer ethylene glycol units and is hydrophilic in nature. PEG is structurally flexible and has high hydration capacity. PEG is biocompatible and is devoid of steric hindrances in its structure. PEG is a Food and Drug Administration (FDA) approved drug conjugates. It is nonimmunogenic and safe. PEG conjugation improves solubility and dissolution of diabetes drug, Gliclazide. PEG is widely used as a reagent in biochemistry and molecular biology experiments. It is used in carbon nanotube functionalization.

Application

Poly(ethylene glycol) has been used:
  • as a component of wheat protoplast isolation and transformation buffer
  • as an additive in suspension cell culture
  • as a component of yeast transformation buffer
  • as a component of crystallization buffer in cysteine protease ATG4B crystallization

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


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Genome editing of bread wheat using biolistic delivery of CRISPR/Cas9 in vitro transcripts or ribonucleoproteins
Liang Z, et al.
Nature Protocols, 13(3), 413-413 (2018)
Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs
Dong S, et al.
Nature Protocols, 5(3), 561-561 (2010)
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
Rasmussen MS, et al.
Autophagy, 13(5), 834-834 (2017)
Characterisation of gliclazide-PEG 8000 solid dispersions
Biswal S, et al.
Tropical Journal of Pharmaceutical Research, 8(5), 260-260 (2009)
Adaptation of the Se301 insect cell line to suspension culture. Effect of turbulence on growth and on production of nucleopolyhedrovius (SeMNPV)
Beas-Catena A, et al.
Cytotechnology, 63(6), 543-552 (2011)

Related Content

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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