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N0761

Sigma-Aldrich

Nicotinic acid

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

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Synonym(s):
3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3
Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
Molecular Weight:
123.11
Beilstein:
109591
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.71

product line

BioReagent

Quality Level

Assay

≥98%

form

powder

mol wt

Mw 123.11 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

color

white to off-white

pH

3.4 (20 °C, 10 g/L)

mp

236-239 °C (lit.)

solubility

1 M NaOH: soluble 50 mg/mL, clear, colorless to very faintly yellow

density

1.473 g/cm3 at 25 °C

application(s)

agriculture

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)
rat ... Chrnb2(54239)

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1 of 4

This Item
N541079838PHR1276
Nicotinic acid BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

Sigma-Aldrich

N0761

Nicotinic acid

Essential+ Grade
Nicotinic acid meets USP testing specifications

Sigma-Aldrich

N5410

Nicotinic acid

-
Nicotinic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

79838

Nicotinic acid

-
Niacin (Nicotinic Acid) Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1276

Niacin (Nicotinic Acid)

-
form

powder

form

powder

form

powder

form

-

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white to off-white

color

white

color

white

color

-

mp

236-239 °C (lit.)

mp

236-239 °C (lit.)

mp

236-239 °C (lit.)

mp

236-239 °C (lit.)

solubility

1 M NaOH: soluble 50 mg/mL, clear, colorless to very faintly yellow

solubility

-

solubility

-

solubility

-

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

379.4 °F - closed cup

Flash Point(C)

193 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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1000309185

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Beat Müller et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20(2), 181-195 (2003-10-11)
A novel methodology for establishing a pharmacological dose-effect relationship of methyl nicotinate, hexyl nicotinate and nicotinic acid acting as peripheral vasodilators in the skin following topical application is investigated. This methodology involves the estimation of the unbound drug concentration in
Paul M Lavigne et al.
Journal of the American College of Cardiology, 61(4), 440-446 (2012-12-26)
This study sought to assess the efficacy of niacin for reducing cardiovascular disease (CVD) events, as indicated by the aggregate body of clinical trial evidence including data from the recently published AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High
John J Albers et al.
Journal of the American College of Cardiology, 62(17), 1575-1579 (2013-08-27)
This study sought to examine the relationship between baseline and on-study apolipoproteins (apo) A-1 and B and lipoprotein(a) [Lp(a)] levels and the development of subsequent cardiovascular (CV) events in the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride
Zhong-Qiu Yu et al.
Autophagy, 16(11), 2036-2051 (2020-01-17)
Macroautophagy (autophagy) is driven by the coordinated actions of core autophagy-related (Atg) proteins. Atg8, the core Atg protein generally considered acting most downstream, has recently been shown to interact with other core Atg proteins via their Atg8-family-interacting motifs (AIMs). However
Sorin Tunaru et al.
Nature medicine, 9(3), 352-355 (2003-02-04)
Nicotinic acid (niacin), a vitamin of the B complex, has been used for almost 50 years as a lipid-lowering drug. The pharmacological effect of nicotinic acid requires doses that are much higher than those provided by a normal diet. Its

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