ESR1

estrogen receptor 1

Synonyms:

ER, ESR, ESRA, ESTRR, Era, NR3A1

Species:

Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), domestic cat ESR1 (552888), dog ESR1 (403640), chicken ESR1 (396099), Thale Cress ESR1 (837856), Horse ESR1 (791249), Zebrafish esr1 (259252), cow ESR1 (407238) ...More

UniProtKB ID:

P03372, Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7

Gene ID:

Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
Mouse(13982) estrogen receptor 1 (alpha)
Rat(24890) estrogen receptor 1
domestic cat(552888) estrogen receptor 1
dog(403640) estrogen receptor 1
chicken(396099) estrogen receptor 1
Thale Cress(837856) ethylene-responsive transcription factor ESR1
Horse(791249) estrogen receptor 1
Zebrafish(259252) estrogen receptor 1
cow(407238) estrogen receptor 1
Goat(100860768) estrogen receptor 1
sheep(443228) estrogen receptor 1
domestic guinea pig(100713276) estrogen receptor 1

Products (202)
Peer Reviewed Papers (1,024)

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Small Molecule - Activator

Product Number

Description

Species

131083

4-Phenylazophenol, 98%,

Species

human

262013

trans-4-Stilbenemethanol, ,

Species

human, rat

S4808

cis-Stilbene, 96%,

Species

human, rat

N0632

β-Nicotinamide adenine dinucleotide sodium salt, ,

Species

human

N8285

β-Nicotinamide adenine dinucleotide, pkg of 10 mg (per vial),

Species

human

Small Molecule - Agonist

Product Number

Description

Species

E1900000

Ethinylestradiol, European Pharmacopoeia (EP) Reference Standard,

Species

human

E1700000

Estrone, European Pharmacopoeia (EP) Reference Standard,

Species

human

M0600000

Mestranol, European Pharmacopoeia (EP) Reference Standard,

Species

human

H6036

1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole, powder, ≥98% (HPLC),

Species

human

E8004

β-Estradiol 17-cypionate, ,

Species

human

Small Molecule - Allosteric Modulator

Product Number

Description

Species

T0015000

Tamoxifen citrate for performance test, European Pharmacopoeia (EP) Reference Standard,

Species

human

1643306

Tamoxifen citrate, United States Pharmacopeia (USP) Reference Standard,

Species

human

BP1225

Tamoxifen citrate, British Pharmacopoeia (BP) Reference Standard,

Species

human

85256

Tamoxifen, analytical standard,

Species

human

T0014000

Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard,

Species

human

Small Molecule - Antagonist

Product Number

Description

Species

442858

4-tert-Octylphenol, analytical standard,

Species

mouse

290823

4-tert-Octylphenol, 97%,

Species

mouse

308501

Benzyl butyl phthalate, 98%,

Species

mouse

C33301

2-Chloro-4,6-diamino-1,3,5-triazine, 95%,

Species

mouse

524980

Dibutyl phthalate, 99%,

Species

mouse

Antibodies

Product Number

Description

Species Reactivity

Application

SAB4500812

Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, mouse

Application

ELISA
immunohistochemistry
western blot

SAB4500813

Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human

Application

ELISA
immunohistochemistry
western blot

SAB4500811

Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, mouse, rat

Application

ELISA
immunohistochemistry
western blot

SAB4301359

Anti-phospho-Estrogen Receptor-α (pSer¹⁰²) antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, mouse, rat

Application

immunohistochemistry
western blot

AMAB90867

Monoclonal Anti-ESR1 antibody produced in mouse, Prestige Antibodies^® Powered by Atlas Antibodies, clone CL1196, purified immunoglobulin, buffered aqueous glycerol solution,

Species Reactivity

human

Application

immunofluorescence
immunohistochemistry
western blot