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Merck

PDE4A

phosphodiesterase 4A, cAMP-specific

동의어:
DPDE2, PDE4, PDE46
:
UniProtKB ID:
Clone ID:
  • Human(5141) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18577) phosphodiesterase 4A, cAMP specific
  • Rat(25638) phosphodiesterase 4A, cAMP-specific
  • sheep(101117505) phosphodiesterase 4A, cAMP-specific
  • Domestic Rabbit(100009247) phosphodiesterase 4A, cAMP-specific
  • Zebrafish(572061) phosphodiesterase 4A, cAMP-specific
  • domestic cat(751107) phosphodiesterase 4A, cAMP-specific
  • dog(100683695) phosphodiesterase 4A, cAMP-specific
  • chicken(769860) phosphodiesterase 4A, cAMP-specific
  • domestic guinea pig(100135594) phosphodiesterase 4A, cAMP-specific
  • cow(512222) phosphodiesterase 4A, cAMP-specific
  • naked mole-rat(101717168) phosphodiesterase 4A, cAMP-specific

Custom & Knockdown Gene Products

Small Molecule - Activator

제품 번호
설명
Rolipram, solid, ≥98% (HPLC),
human, mouse, rat

Small Molecule - Antagonist

제품 번호
설명
4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one, solid,
human, rat
Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Theophylline, European Pharmacopoeia (EP) Reference Standard,
human
Theophylline, United States Pharmacopeia (USP) Reference Standard,
human
Theophylline, British Pharmacopoeia (BP) Reference Standard,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PDE4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-PDE4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry

Small Molecule - Inhibitor

제품 번호
설명
Ibudilast, ≥99% (HPLC), solid,
human
Zaprinast, solid,
human
Roflumilast, ≥98% (HPLC),
human
Amlexanox, ≥98% (HPLC),
human
7-(2,3-Dihydroxypropyl)theophylline, ,
human

Proteins

제품 번호
설명
PDE4A1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
human
PDE4A4B active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥40% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PDE4A (3),
human
MISSION® esiRNA, targeting human PDE4A,
human
MISSION® esiRNA, targeting human PDE4A (2),
human
MISSION® esiRNA, targeting mouse Pde4a,
mouse