PRKACB
protein kinase, cAMP-dependent, catalytic, beta
Synonyms:
PKACB
Species:
Human PRKACB (5567), Mouse Prkacb (18749), Rat Prkacb (293508), dog PRKACB (479975), chicken PRKACB (424542), naked mole-rat Prkacb (101721558), cow PRKACB (282323), domestic cat PRKACB (101095353), sheep PRKACB (101108785), Zebrafish prkacb (100538234)
UniProtKB ID:
Gene ID:
- Human(5567) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2011]
- Mouse(18749) protein kinase, cAMP dependent, catalytic, beta
- Rat(293508) protein kinase, cAMP dependent, catalytic, beta
- dog(479975) protein kinase, cAMP-dependent, catalytic, beta
- chicken(424542) protein kinase, cAMP-dependent, catalytic, beta
- naked mole-rat(101721558) protein kinase, cAMP-dependent, catalytic, beta
- cow(282323) protein kinase, cAMP-dependent, catalytic, beta
- domestic cat(101095353) protein kinase, cAMP-dependent, catalytic, beta
- sheep(101108785) protein kinase, cAMP-dependent, catalytic, beta
- Zebrafish(100538234) protein kinase, cAMP-dependent, catalytic, beta
- domestic guinea pig(100712694) protein kinase, cAMP-dependent, catalytic, beta
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PRKACB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-PRKACB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-PRKACB antibody produced in mouse, clone 2G8-1D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-phospho-PKA Catalytic β subunit (Ser338) Antibody, Upstate®, from rabbit,
Species Reactivity
mouse
Application
western blot
Anti-phospho-PKA CAT (pThr197) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Protein Kinase A Catalytic Subunit β, Active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human