PRKACB
protein kinase, cAMP-dependent, catalytic, beta
Sinónimos:
PKACB
Especie:
Human PRKACB (5567), Mouse Prkacb (18749), Rat Prkacb (293508), dog PRKACB (479975), chicken PRKACB (424542), naked mole-rat Prkacb (101721558), cow PRKACB (282323), domestic cat PRKACB (101095353), sheep PRKACB (101108785), Zebrafish prkacb (100538234)
ID UniProtKB:
ID del gen:
- Human(5567) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2011]
- Mouse(18749) protein kinase, cAMP dependent, catalytic, beta
- Rat(293508) protein kinase, cAMP dependent, catalytic, beta
- dog(479975) protein kinase, cAMP-dependent, catalytic, beta
- chicken(424542) protein kinase, cAMP-dependent, catalytic, beta
- naked mole-rat(101721558) protein kinase, cAMP-dependent, catalytic, beta
- cow(282323) protein kinase, cAMP-dependent, catalytic, beta
- domestic cat(101095353) protein kinase, cAMP-dependent, catalytic, beta
- sheep(101108785) protein kinase, cAMP-dependent, catalytic, beta
- Zebrafish(100538234) protein kinase, cAMP-dependent, catalytic, beta
- domestic guinea pig(100712694) protein kinase, cAMP-dependent, catalytic, beta
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-phospho-PKA Catalytic β subunit (Ser338) Antibody, Upstate®, from rabbit,
Reactividad de especies
mouse
Aplicación
western blot
Monoclonal Anti-PRKACB antibody produced in mouse, clone 2G8-1D12, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
Anti-phospho-PKA C (Thr197) Antibody, clone 24GB1650, Rabbit Monoclonal, clone 24GB1650, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
western blot
western blot
Small Molecule - Inhibitor
Proteins
Número de producto
Descripción
Especie
Protein Kinase A Catalytic Subunit β, Active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human