H7660
Heregulin-β1 (EGF Domain) human
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
Synonym(s):
HRG-β1
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About This Item
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biological source
human
Quality Level
recombinant
expressed in E. coli
Assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
<0.50 ng/mL
mol wt
predicted mol wt 8 kDa
packaging
pkg of 10 and 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
Biochem/physiol Actions
Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases.
Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.
Analysis Note
The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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