- A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress.
A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress.
Biomolecules & therapeutics (2017-05-31)
Jeong Eon Park, Mei Jing Piao, Kyoung Ah Kang, Kristina Shilnikova, Yu Jae Hyun, Sei Kwan Oh, Yong Joo Jeong, Sungwook Chae, Jin Won Hyun
PMID28554201
要旨
Benzylideneacetophenone derivative (1E)-1-(4-hydroxy-3-methoxyphenyl) hept-1-en-3-one (JC3) elicited cytotoxic effects on MDA-MB 231 human breast cancer cells-radiation resistant cells (MDA-MB 231-RR), in a dose-dependent manner, with an IC