294381
N,N′-(1,2-Dihydroxyethylene)bisacrylamide
97%
동의어(들):
N,N′-Bisacryloyl-1,2-dihydroxy-1,2-ethylenediamine, DHEBA
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
Linear Formula:
[H2C=CHCONHCH(OH)-]2
CAS Number:
Molecular Weight:
200.19
Beilstein:
1941875
EC Number:
MDL number:
UNSPSC 코드:
12162002
PubChem Substance ID:
NACRES:
NA.23
추천 제품
분석
97%
양식
solid
mp
156 °C (dec.) (lit.)
SMILES string
OC(NC(=O)C=C)C(O)NC(=O)C=C
InChI
1S/C8H12N2O4/c1-3-5(11)9-7(13)8(14)10-6(12)4-2/h3-4,7-8,13-14H,1-2H2,(H,9,11)(H,10,12)
InChI key
ZMLXKXHICXTSDM-UHFFFAOYSA-N
일반 설명
N,N′-(1,2-Dihydroxyethylene)bisacrylamide, commonly referred to as DHEBA or bis-acrylamide. It is used as a crosslinking agent in various biomedical applications. Its structure includes two acrylamide groups linked by a dihydroxyethylene bridge, which enhances its reactivity and ability to form hydrogels. In the biomedical field, DHEBA is primarily utilized in the synthesis of hydrogels that can be used for drug delivery systems, tissue engineering scaffolds, and biosensors. The hydrophilic nature of the compound allows for the formation of hydrogels that can retain water and biological molecules, making them suitable for applications that require biocompatibility and bioactivity.
애플리케이션
N,N′-(1,2-Dihydroxyethylene)bisacrylamide can be used as:
- A crosslinker in the synthesis of hydrogel microparticles with a porous hydrogel structure. This porosity is essential for enhancing biomolecule accessibility and mass transport, which are critical for the performance of biosensing applications.
- A cross-linking agent in the preparation of molecularly imprinted polymers, that can selectively bind to oxidized low-density lipoprotein (oxLDL). The cross-linking enhances the mechanical stability and structural integrity of the polymer matrix.
- A cross-linking agent in the preparation of hydrogels or polymer matrices that support biological imaging applications.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Gisela Giorgi et al.
Experimental physiology, 100(10), 1199-1216 (2015-06-06)
What is the central question of this study? The aim was to explore the role and hitherto unclear mechanisms of action of iron proteins in protecting the lung against the harmful effects of iron accumulation and the ability of pulmonary
Suticha Chunta et al.
Analytica chimica acta, 1116, 27-35 (2020-05-12)
Oxidized-low-density lipoprotein (oxLDL) is well-recognized as an actual patho-atherogenic lipoprotein: elevated serum concentration of oxLDL increases the risk for developing atherosclerosis, leading to coronary artery disease (CAD). Herein, we report an approach for sensing oxLDL directly in serum with molecularly
Suticha Chunta et al.
Talanta, 221, 121549-121549 (2020-10-21)
Very-low-density lipoprotein (VLDL) contributes to the buildup of atherosclerotic plaque in the arteries and can lead to coronary heart disease. In clinical laboratory testing, the cholesterol content of VLDL (VLDL-C) cannot be assessed directly by the enzymatic colorimetric assay as
Martin Zeilinger et al.
Sensors (Basel, Switzerland), 19(10) (2019-05-28)
Food standards and quality control are important means to ensure public health. In the last decade, melamine has become a rather notorious example of food adulteration: Spiking products with low-cost melamine in order to feign high amino acid content exploits
U Neumann et al.
Analytical biochemistry, 206(1), 1-5 (1992-10-01)
A simple and rapid method for the quantitation of proteins separated either by sodium dodecyl sulfate-electrophoresis or by isoelectric focusing in slab gels is presented. The method is based on the solubility of polyacrylamide gels crosslinked with N, N'-1, 2-dihydroxyethylenebisacrylamide
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