MilliporeSigma
All Photos(3)

146072

Sigma-Aldrich

N,N′-Methylenebis(acrylamide)

99%

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
Bis-acrylamide
Linear Formula:
(H2C=CHCONH)2CH2
CAS Number:
Molecular Weight:
154.17
EC Number:
MDL number:
PubChem Substance ID:
Flavis number:
7.107
NACRES:
NB.22

vapor density

5.31 (vs air)

Quality Level

Assay

99%

form

powder

mp

>300 °C (lit.)

solubility

water: soluble 20 g/L at 20 °C

storage temp.

2-8°C

SMILES string

C=CC(=O)NCNC(=O)C=C

InChI

1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)

InChI key

ZIUHHBKFKCYYJD-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
M7279M1533A2917
Acrylamide/Bis-acrylamide BioReagent, for molecular biology, 19:1 (ratio)

Sigma-Aldrich

A2917

Acrylamide/Bis-acrylamide

Essential+ Grade
vapor density

5.31 (vs air)

vapor density

-

vapor density

-

vapor density

-

assay

99%

assay

≥99.5%

assay

-

assay

-

mp

>300 °C (lit.)

mp

-

mp

-

mp

-

solubility

water: soluble 20 g/L at 20 °C

solubility

-

solubility

-

solubility

-

N N′-Methylenebisacrylamide; Bis-acrylamide, SDS-PAGE, hydrogels, electrophoresis, acrylamide, gel.acrylamide, N N′-Methylenebis(acrylamide) 99%, MBA; NAPP

-

-

-

General description

N,N′-Methylenebis(acrylamide) is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel. It is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.

Application

N,N′-Methylenebis(acrylamide) has been used in gel preparation. It has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.
Cross-linking agent for preparation of polyacrylamides.

related product

Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Carc. 1B - Muta. 1B - Repr. 2 - STOT RE 1 Oral

Target Organs

Peripheral nervous system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 8

1 of 8

Acrylamide purum, ≥98.0% (GC)

Sigma-Aldrich

01700

Acrylamide

Sodium acrylate 97%

Sigma-Aldrich

408220

Sodium acrylate

N-Isopropylacrylamide ≥99%

Sigma-Aldrich

731129

N-Isopropylacrylamide

Acrylamide for synthesis

Sigma-Aldrich

8.00830

Acrylamide

Ammonium persulfate ACS reagent, ≥98.0%

Sigma-Aldrich

248614

Ammonium persulfate

Edwin Makhado et al.
International journal of biological macromolecules, 119, 255-269 (2018-07-23)
In the present study, facile and efficient method was adopted for the synthesis of graft copolymer hydrogel by graft copolymerization of acrylic acid (AA) onto xanthan gum (XG) biopolymer in the presence of N,N'-Methylenebisacrylamide (MBA), and ammonium persulfate (APS) as
Timothy Olding et al.
Journal of medical physics, 36(1), 3-14 (2011-03-25)
This paper explores the combination of cone beam optical computed tomography with an N-isopropylacrylamide (NIPAM)-based polymer gel dosimeter for three-dimensional dose imaging of small field deliveries. Initial investigations indicate that cone beam optical imaging of polymer gels is complicated by
Carl Julien et al.
Methods in molecular biology (Clifton, N.J.), 849, 473-491 (2012-04-25)
Tau is a highly soluble microtubule-associated protein (MAP) that is abundant in the central nervous system and expressed mainly in neuronal axons. Intracellular aggregates of insoluble tau protein are present in a group of neurodegenerative diseases called tauopathies, which include
Damla Keskin et al.
Biomacromolecules, 20(1), 243-253 (2018-12-05)
Bacterial infection is a severe problem especially when associated with biomedical applications. This study effectively demonstrates that poly- N-isopropylmethacrylamide based microgel coatings prevent bacterial adhesion. The coating preparation via a spraying approach proved to be simple and both cost and
Ruohong Shi et al.
Small (Weinheim an der Bergstrasse, Germany), 16(37), e2002946-e2002946 (2020-08-11)
Hydrogels with the ability to change shape in response to biochemical stimuli are important for biosensing, smart medicine, drug delivery, and soft robotics. Here, a family of multicomponent DNA polymerization motor gels with different polymer backbones is created, including acrylamide-co-bis-acrylamide

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service