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Merck
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주요 문서

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760668

Sigma-Aldrich

Dibenzocyclooctyne-maleimide

for Copper-free Click Chemistry

동의어(들):

DBCO-maleimide

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C25H21N3O4
Molecular Weight:
427.45
MDL number:
MFCD22380750
UNSPSC 코드:
12352111
PubChem Substance ID:
329766887
NACRES:
NA.22

양식

solid

반응 적합성

reaction type: click chemistry
reagent type: cross-linking reagent

작용기

maleimide

저장 온도

−20°C

SMILES string

O=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O

InChI

1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)

InChI key

NHFQNAGPXIVKND-UHFFFAOYSA-N

관련 카테고리

애플리케이션

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:
  • Protein-peptide conjugates
  • Antibody-enzyme or antibody-drug conjugates
  • Protein or peptide-oligonucleotide conjugates
  • Surface modification

픽토그램

Environment
GHS09

신호어

Warning

유해 및 위험 성명서

H400

예방조치 성명서

P273

Hazard Classifications

Aquatic Acute 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number
MKCW1170
MKCW5477
MKCT1472
MKCR9310
MKCR5605

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문서

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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