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Merck
모든 사진(4)

주요 문서

C1761

Sigma-Aldrich

Chorismic acid from Enterobacter aerogenes

≥80%

동의어(들):

trans-3-([1-Carboxyethenyl]oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid

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About This Item

실험식(Hill 표기법):
C10H10O6
CAS Number:
Molecular Weight:
226.18
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

≥80%

양식

powder

배송 상태

dry ice

저장 온도

−20°C

SMILES string

O[C@@H]1C=CC(=C[C@H]1OC(=C)C(O)=O)C(O)=O

InChI

1S/C10H10O6/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11/h2-4,7-8,11H,1H2,(H,12,13)(H,14,15)/t7-,8-/m1/s1

InChI key

WTFXTQVDAKGDEY-HTQZYQBOSA-N

관련 카테고리

애플리케이션

Chorismic acid is a metabolite generally used in the study of chorismate-prephenate rearrangement and to synthesize chorismate derivatives.
Intermediate in the biosynthesis of aromatic amino acids via the shikimate pathway.

픽토그램

Health hazardExclamation mark

신호어

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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문서 라이브러리 방문

Gamma Chi et al.
Biochemistry, 51(24), 4868-4879 (2012-05-23)
MbtI is the salicylate synthase that catalyzes the first committed step in the synthesis of the iron chelating compound mycobactin in Mycobacterium tuberculosis. We previously developed a series of aromatic inhibitors against MbtI based on the reaction intermediate for this
Expanding the genetic code.
Wang, Lei and Schultz, Peter G
Angewandte Chemie (International Edition in English), 44(1), 34-66 (2005)
The mechanism of rearrangement of chorismic acid and related compounds.
Gajewski, Joseph J et al.
Journal of the American Chemical Society, 109(4), 1170-1186 (1987)
Alexandra Choutko et al.
Protein science : a publication of the Protein Society, 21(11), 1672-1681 (2012-08-18)
The protein chorismate mutase MtCM from Mycobacterium tuberculosis catalyzes one of the few pericyclic reactions known in biology: the transformation of chorismate to prephenate. Chorismate mutases have been widely studied experimentally and computationally to elucidate the transition state of the
Nivedita Nagachar et al.
FEMS microbiology letters, 308(2), 159-165 (2010-05-22)
Mycobacterium smegmatis acquires extracellular iron using exochelin, mycobactin and carboxymycobactin. The latter two siderophores are synthesized from salicylic acid, which, in turn, is derived from chorismic acid in the shikimic acid pathway. To understand the conversion mechanism of chorismic acid

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