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57400

Sigma-Aldrich

Indole-3-propionic acid

≥99.0% (T)

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Synonym(s):
3-(3-Indolyl)propanoic acid, 3-(3-Indolyl)propionic acid, IPA, NSC 3252, NSC 47831
Empirical Formula (Hill Notation):
C11H11NO2
CAS Number:
Molecular Weight:
189.21
Beilstein:
147733
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥99.0% (T)

form

solid

ign. residue

≤0.1%

mp

~133 °C

SMILES string

OC(=O)CCc1c[nH]c2ccccc12

InChI

1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14)

Inchi Key

GOLXRNDWAUTYKT-UHFFFAOYSA-N

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This Item
I55085741057310
Indole-3-butyric acid ≥98.0% (T)

Sigma-Aldrich

57310

Indole-3-butyric acid

form

solid

form

-

form

solid

form

-

mp

~133 °C

mp

145-146 °C (lit.)

mp

-

mp

122-125 °C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

ign. residue

≤0.1%

ign. residue

-

ign. residue

-

ign. residue

-

Biochem/physiol Actions

Studied as an adjunct to improve perfusion after liver transplant.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Zhongqi Cheng et al.
Environmental science & technology, 39(19), 7662-7666 (2005-10-26)
Field and laboratory experiments were conducted to study the potential use of Fe filings to remove monomethyl arsenate (MMA) and dimethyl arsenate (DMA) from contaminated waters. Batch experiments show that the affinity of MMAfor Fe filings is comparable to that
Bernd Kuhn et al.
Bioorganic & medicinal chemistry letters, 16(15), 4016-4020 (2006-06-02)
In the quest for novel PPARalpha/gamma co-agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we have used a structure-based design approach to identify propionic acids with a 1,5-disubstituted indole scaffold as potent PPARalpha/gamma activators. Compounds
Y J Chyan et al.
The Journal of biological chemistry, 274(31), 21937-21942 (1999-07-27)
Widespread cerebral deposition of a 40-43-amino acid peptide called the amyloid beta-protein (Abeta) in the form of amyloid fibrils is one of the most prominent neuropathologic features of Alzheimer's disease. Numerous studies suggest that Abeta is toxic to neurons by
Katja Zuther et al.
Molecular microbiology, 68(1), 152-172 (2008-03-04)
Tryptophan is a precursor for many biologically active secondary metabolites. We have investigated the origin of indole pigments first described in the pityriasis versicolor-associated fungus Malassezia furfur. Some of the identified indole pigments have properties potentially explaining characteristics of the
Paul E Bendheim et al.
Journal of molecular neuroscience : MN, 19(1-2), 213-217 (2002-09-06)
The accumulation of amyloid-beta and concomitant oxidative stress are major pathogenic events in Alzheimer's disease. Indole-3-propionic acid (IPA, OXIGON) is a potent anti-oxidant devoid of pro-oxidant activity. IPA has been demonstrated to be an inhibitor of beta-amyloid fibril formation and

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