추천 제품
생물학적 소스
mouse
Quality Level
클론
CC-1, monoclonal
형태
liquid
포함
≤0.1% sodium azide
종 반응성
human, mouse, rat
제조업체/상표
Calbiochem®
저장 조건
do not freeze
기술
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry (frozen sections): suitable
dilution
(Free-floating SectionsParaffin Sections)
동형
IgG2b
배송 상태
wet ice
저장 온도
2-8°C
일반 설명
Recognizes APC in oligodendrocytes and astrocytes.
- Antibody Target Gene Symbol: APC
- Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC
- Entrez Gene Name: adenomatous polyposis coli
- Hu Entrez ID: 324 (Related Antibodies: ST1150, OP62, OP47L, OP44)
- Mu Entrez ID: 11789
- RatEntrez ID: 24205
면역원
a recombinant protein consisting of amino acids 1-226 of APC
애플리케이션
Frozen Sections (5 µg/ml) Immunofluorescence (5 µg/ml) Paraffin Sections (5 µg/ml, heat pre-treament required) Immunocytochemistry (see application references) Free Floating Sections (see application references)
Well suited for IHC and IF studies of oligodendrocytes and optic nerves due to the antibody′s staining of the cell body as opposed to the myelinated processes. Both frozen sections and formalin-fixed, paraffin-embedded brain sections can be used. Antibody should be titrated for optimal results in individual systems.
Well suited for IHC and IF studies of oligodendrocytes and optic nerves due to the antibody′s staining of the cell body as opposed to the myelinated processes. Both frozen sections and formalin-fixed, paraffin-embedded brain sections can be used. Antibody should be titrated for optimal results in individual systems.
포장
Please refer to vial label for lot-specific concentration
경고
Toxicity: Standard Handling
물리적 형태
In 50 mM sodium phosphate buffer, 0.2% gelatin.
분석 메모
Negative control: MOPC 21 cells
Positive control: Purkinje cells or cerebellum tissue
Positive control: Purkinje cells or cerebellum tissue
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
K W Kinzler et al.
Science (New York, N.Y.), 251(4999), 1366-1370 (1991-03-15)
Recent studies have suggested the existence of a tumor suppressor gene located at chromosome region 5q21. DNA probes from this region were used to study a panel of sporadic colorectal carcinomas. One of these probes, cosmid 5.71, detected a somatically
R V Bhat et al.
Glia, 17(2), 169-174 (1996-06-01)
Mutations of the adenomatous polyposis coli (APC) tumor suppressor gene have been linked to familial polyposis, an inherited predisposition to colon cancer, and a high percentage of sporadic colon adenomas. Although this gene is best known for its role in
The APC gene product in normal and tumor cells
Smith, K.J., et al.
Proceedings of the National Academy of Sciences, 90, 2846-2850 (1993)
J Groden et al.
Cell, 66(3), 589-600 (1991-08-09)
DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes (DP1, SRP19, and DP2.5) located within a 100 kb region deleted in two of the patients. The intron-exon boundary sequences were defined for
L K Su et al.
Cancer research, 53(12), 2728-2731 (1993-06-15)
Germline mutations of the APC gene are responsible for familial adenomatous polyposis, an autosomal dominant inherited predisposition to colorectal tumors. Mutation of the APC gene is also an early, if not initiating, event for sporadic colorectal tumorigenesis. In both cases
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