추천 제품
Grade
analytical standard
Quality Level
제품 라인
VETRANAL®
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
forensics and toxicology
pharmaceutical (small molecule)
형식
neat
SMILES string
Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F
InChI
1S/C14H11F3N2O2/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12/h2-7H,1H3,(H,18,19)(H,20,21)
InChI key
NOOCSNJCXJYGPE-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Flunixin is a potent nonsteroidal anti-inflammatory drug, primarily used as an anti-inflammatory agent and analgesic for the short-term treatment of moderate pain and inflammation in farm animals. It is also effective in inhibiting the synthesis of prostaglandins.
Flunixin is classified under the group of non-steroidal anti-inflammatory drugs (NSAIDs).
애플리케이션
Flunixin may be used as a reference standard for the determination of NSAID drug, flunixin in biological samples using high-performance liquid chromatography with diode array detection (HPLC-DAD)/particle beam mass spectrometry (PB-MS)/atmospheric pressure ionization mass spectrometry (API-MS) and gas chromatography coupled to mass spectrometry (GC-MS).
Flunixin may be used as an analytical reference standard for the determination of flunixin in:
- Bovine muscle samples by hydrophilic interaction liquid chromatography-electrospray-tandem mass spectrometry (HILIC-ESI-MS/MS) equipped with selected reaction monitoring (SRM) detection.
- Animal tissues by dispersive-solid phase extraction (d-SPE) and enhanced matrix removal for lipids (EMR-L), followed by analysis using ultra-high performance liquid chromatography-triple quadrupole or quadrupole-time-of-flight (UHPLC-QqQ or UHPLC-Q/TOF) methods in conjunction with ESI-MS/MS operating on multiple reaction monitoring (MRM) mode of detection as well as ESI-LC-MS/MS with SRM detection mode.
- Porcine muscle samples by ESI-LC-MS/MS with MRM detection mode.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
추천 제품
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
법적 정보
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
이미 열람한 고객
Comparison of veterinary drug residue results in animal tissues by ultrahigh-performance liquid chromatography coupled to triple quadrupole or quadrupole-time-of-flight tandem mass spectrometry after different sample preparation methods, including use of a commercial lipid removal product.
Anumol T, et al.
Analytical and Bioanalytical Chemistry, 409(10), 2639-2653 (2017)
J E Tomlinson et al.
Equine veterinary journal, 37(1), 75-80 (2005-01-18)
Recent studies have shown that flunixin prevented recovery of equine jejunum post ischaemia. However, the use of a purported cyclooxygenase (COX)-2 preferential inhibitor, etodolac, also prevented recovery. These findings may have implications for the use of nonsteroidal anti-inflammatory drugs in
Robinson EN and Sprayberry.AK
Current Therapy in Equine Medicine (2009)
Saunders Handbook of Veterinary Drugs - E-Book (2015)
Development of a Rapid Method for the Confirmatory Analysis of Flunixin Residue in Animal Tissues Using Liquid Chromatography-Tandem Mass Spectrometry.
Liu ZY, et al.
Food Analytical Methods, 8(2), 352-362 (2015)
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