32463
5-Hydroxyflunixin
VETRANAL®, analytical standard
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All Photos(2)
Synonym(s):
5-Hydroxy-2-(2-methyl-3-trifluoromethylanilino)nicotinic acid, 5-Hydroxy-2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}-3-pyridinecarboxylic acid
Empirical Formula (Hill Notation):
C14H11F3N2O3
CAS Number:
Molecular Weight:
312.24
Beilstein/REAXYS Number:
9575875
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cc1c(Nc2ncc(O)cc2C(O)=O)cccc1C(F)(F)F
InChI
1S/C14H11F3N2O3/c1-7-10(14(15,16)17)3-2-4-11(7)19-12-9(13(21)22)5-8(20)6-18-12/h2-6,20H,1H3,(H,18,19)(H,21,22)
InChI key
JSXNJGKWSWRIGA-UHFFFAOYSA-N
Related Categories
General description
Flunixin (FLU) is a non-steroidal anti-inflammatory drug (NSAID). It is a nicotinic acid derivative, and is involved in inhibiting the enzyme cyclooxygenase in the arachidonic acid cascade. It is anti-pyretic and non-narcotic analgesic in nature, and finds application in veterinary medicine, where it is used to treat a wide variety of disorder in diverse species. This drug can be used to reduce pain and inflammation associated with colic in horses, musculoskeletal disorders, and infectious diseases in cattle. It can also be used as an aid in the treatment of mastitis-metritis-agalactia syndrome in sows. 5-hydroxyflunixin (5OHFLU) is the main metabolite of Flunixin (FLU).
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Recommended products
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Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
wgk_germany
WGK 3
Certificates of Analysis (COA)
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Jessica L Bates et al.
BMC veterinary research, 16(1), 211-211 (2020-06-24)
Flunixin meglumine (FM) was investigated for the effectiveness of plasma, oral fluid, and urine concentrations to predict tissue residue depletion profiles in finishing-age swine, along with the potential for untreated pigs to acquire tissue residues following commingled housing with FM-treated
M Cheema et al.
Journal of dairy science, 100(11), 8670-8679 (2017-09-18)
Casein proteins (α
Shubhashis Chakrabarty et al.
Rapid communications in mass spectrometry : RCM, 34(20), e8876-e8876 (2020-07-07)
Electrospray ionization mass spectrometry (ESI-MS) in conjunction with liquid chromatography (LC) can provide accurate quantitative data, but it is not well-suited for the rapid screening (RS) of analytes incurred into complex matrices. This study was designed to determine the usefulness
Weilin L Shelver et al.
Journal of agricultural and food chemistry, 64(1), 336-345 (2015-12-24)
Twenty cull dairy cows (645 ± 83 kg) were treated with 2.2 mg/kg bw flunixin by intravenous (IV) or intramuscular (IM) administration with, or without, exposure to lipopolysaccharide in a two factor balanced design. The usefulness of screening assays to
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