F0429

Flunixin meglumine

≥98% (HPLC)

• Synonym(s): 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt, Banamine
• Empirical Formula (Hill Notation): C₁₄H₁₁F₃N₂O₂·C₇H₁₇NO₅
• CAS Number: 42461-84-7
• Molecular Weight: 491.46
• EC Number: 255-836-0
• MDL number: MFCD01725419
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724478
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• mp: 136.6-137.4 °C
• solubility: H₂O: freely soluble
• storage temp.: room temp
• SMILES string: CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F
• InChI: 1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
• InChI key: MGCCHNLNRBULBU-WZTVWXICSA-N

Description

Application

Flunixin meglumine has been used as a nonsteroidal anti-inflammatory drug standard in electrospray ionization mass spectrometry (LC-ESI/MS).

Flunixin meglumine (IC₅₀ = 1 nM) can be used as a drug for animals for the management of intestinal ischaemia, colic, and endotoxemia in horses.

Biochem/physiol Actions

Flunixin meglumine is a nonsteroidal anti-inflammatory drug, which blocks prostaglandin synthesis.

COX1, COX2 and PLA2 inhibitor non-narcotic analgesic, anti-pyretic, anti-inflammatory.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves