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Merck
모든 사진(2)

주요 문서

15721

Sigma-Aldrich

Polydatin

≥95% (HPLC)

동의어(들):

Piceid, Reservatrol-3-β-mono-D-glucoside, Resveratrol 3-O-β-D-glucopyranoside

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About This Item

실험식(Hill 표기법):
C20H22O8
CAS Number:
Molecular Weight:
390.38
Beilstein:
54837
UNSPSC 코드:
12352201
PubChem Substance ID:
NACRES:
NA.25

Quality Level

분석

≥95% (HPLC)

형태

powder

광학 활성

[α]1/D -66.0±2.0° in ethanol

구성

carbon, 60.5-62.5%

저장 온도

2-8°C

SMILES string

OCC1O[C@@H](Oc2cc(O)cc(\C=C\c3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16?,17-,18+,19-,20-/m1/s1

InChI key

HSTZMXCBWJGKHG-AEGFYQLOSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Polydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities. Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibits therapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the direct protection of neurons.

생화학적/생리학적 작용

Stilbene found in medicinal herbs. Antioxidant, anti-inflammatory and neuroprotective.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

M J Wu et al.
International journal of immunopathology and pharmacology, 25(4), 923-934 (2013-01-10)
Fulminant hepatic failure (FHF) is a devastating clinical syndrome with extremely poor prognosis and high mortality. Therefore, better treatment is urgently needed. Polydatin (PD), a traditional anti-inflammatory drug, has been described to protect against liver injury induced by certain hepatotoxins.
Hong Zhang et al.
PloS one, 7(9), e46574-e46574 (2012-10-03)
Polydatin is one of main compounds in Polygonum cuspidatum, a plant with both medicinal and nutritional value. The possible hepatoprotective effects of polydatin on acute liver injury mice induced by carbon tetrachloride (CCl(4)) and the mechanisms involved were investigated. Intraperitoneal
Giampietro Ravagnan et al.
Inflammation, 36(1), 26-34 (2012-09-08)
It is well known that human keratinocytes produce the anti-microbial peptide β-defensin 2. Its production is enhanced by pathogenic microorganisms or other environmental stressors. In this study, we evaluated the effect of resveratrol, a polyphenol found in several dietary source
Xingmin Wang et al.
Expert opinion on investigational drugs, 22(2), 169-179 (2012-12-18)
The aim of the study was find out whether neuronal mitochondrial injury does take place in severe shock and to explore effective therapy for severe shock. Rats were divided in the following group: sham, shock + normal saline (NS), shock
Maria Rotches-Ribalta et al.
Pharmacological research, 66(5), 375-382 (2012-08-22)
A pharmacokinetic study of the metabolic profile of resveratrol has been performed in healthy men after moderate red wine (RW) consumption. The bioavailability of resveratrol is highly influenced by several factors such as the food matrix and, therefore, this study

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