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Merck
모든 사진(1)

주요 문서

A5486

Sigma-Aldrich

Azoxymethane

13.4 M, ≥98%

동의어(들):

AOM

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About This Item

Linear Formula:
CH3N=N(→O)CH3
CAS Number:
Molecular Weight:
74.08
MDL number:
UNSPSC 코드:
12352124
PubChem Substance ID:
NACRES:
NA.25

Quality Level

분석

≥98%

양식

liquid

구성

methylene chloride, ≤1% (solvent)

저장 조건

(Keep container tightly closed in a dry and well-ventilated place.)

농도

13.4 M

색상

colorless

bp

97-99 °C (lit.)

density

0.991 g/mL at 25 °C (lit.)

응용 분야

genomic analysis

저장 온도

−20°C

SMILES string

C\N=[N+](/C)[O-]

InChI

1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+

InChI key

DGAKHGXRMXWHBX-ONEGZZNKSA-N

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일반 설명

Azoxymethane (AOM) is a potent laboratory chemical used to study cancer initiation, progression, and prevention, particularly in the colon. It acts as both a carcinogen, triggering tumor formation, and a gene mutation agent, causing specific alterations in DNA.

애플리케이션

Azoxymethane (AOM), a gene mutation agent, may be used with dextran sulfate sodium (DSS) to create cancer models in laboratory animals which can be used to study mechanisms of cancer progression and chemoprevention.

생화학적/생리학적 작용

Carcinogen that induces O6-methylguanine adducts in DNA leading to G→A transitions. Induces tumorigenesis in the colon of laboratory animals and is used to study the mechanism of cancer progression and chemoprevention.

특징 및 장점

Versatile and adaptable for a wide variety of laboratory and research applications.

기타 정보

For additional information on our range of Biochemicals, please complete this form.
It is critical to determine the correct dosage of Azoxymethane for the experimental design to avoid premature death of laboratory animals.

관련 제품

제품 번호
설명
가격

픽토그램

FlameSkull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point (°F)

75.2 °F

Flash Point (°C)

24 °C


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