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Sigma-Aldrich

Dextran sulfate sodium salt

Mw 7,000-20,000

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NACRES:
NA.25

form

powder

Quality Level

mol wt

Mw 7,000-20,000

loss

≤10% loss on drying

color

white

useful pH range

6.0-8 (10 g/L)

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

storage temp.

room temp

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This Item
6757875027RES2029D-A7
color

white

color

-

color

colorless

color

-

useful pH range

6.0-8 (10 g/L)

useful pH range

6.0-8.0 (10 g/L)

useful pH range

6.0-8.0 (10 g/L)

useful pH range

-

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

-

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

-

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

400

General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Application

Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Biochem/physiol Actions

Dextran sulfate inhibits the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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25G
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M Baba et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(16), 6132-6136 (1988-08-01)
The sulfated polysaccharides dextran sulfate and heparin have proved to be potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) in vitro. Dextran sulfate (Mr 5000) and heparin (Mr 15,000) completely protected MT-4 cells against HIV-1-induced cytopathogenicity at

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