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Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

low sulfate content, Mr ~40,000

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CAS Number:
MDL number:
NACRES:
NA.25

biological source

(Leuconostoc spp)

Quality Level

form

powder

quality

low sulfate content

mol wt

Mr ~40,000

composition

Sulfur Content, 8-13%

loss

≤10% loss on drying

color

white to off-white

useful pH range

6.0-8 (10 g/L)

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

storage temp.

room temp

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This Item
D692431395D8787
form

powder

form

powder

form

powder

form

powder or crystals

color

white to off-white

color

white to off-white

color

-

color

white to off-white

useful pH range

6.0-8 (10 g/L)

useful pH range

5.5 - 8.0

useful pH range

6.0-8.0 (10 g/L)

useful pH range

-

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL

solubility

H2O: freely soluble 50 mg/mL, clear

solubility

H2O: 100 mg/mL

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

-

General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Application

Dextran sulfate increases binding of epithelial cells and lymphocytes to extracellular matrix proteins including fibronectin and laminin. In addition, dextran sulfate altered expreβion of cell surface receptors integrins.
Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Preparation Note

Sigma dextrans are derived from Leuconostoc mesenteroides.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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J Ni et al.
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FITC-labelled polysaccharides

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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