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31395

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

Mr ~500,000

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CAS Number:
MDL number:
NACRES:
NA.21

biological source

(Leuconostoc spp.)

Quality Level

form

powder

mol wt

Mr ~500,000

composition

Sulfur Content, 16.0-19.0% (dry basis)

manufacturer/tradename

EDQM

useful pH range

6.0-8.0 (10 g/L)

solubility

H2O: freely soluble 50 mg/mL, clear

anion traces

chloride (Cl-): ≤100 mg/kg

cation traces

Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤100 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

storage temp.

room temp

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Application

Dextran sulfate sodium salt from Leuconostoc sp. was used as a test compound for studying the heparin and dextran sulphate interaction with alkali ions. It was used for releasing DNA from DNA-histone complexes.

Biochem/physiol Actions

Dextran is a mixture of glucose polymers of varying size and geometry. Dextran in the form of dextran sulfate acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength.The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.

Preparation Note

prepared from dextran with Mr ~500,000

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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