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D4911

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

mol wt 6,500-10,000

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CAS Number:
MDL number:
NACRES:
NA.21

biological source

bacterial (Leuconostoc)

Quality Level

form

powder

mol wt

6,500-10,000

composition

Sulfur Content, 16.0-20.0%

color

white to light yellow

useful pH range

6.0-8 (10 g/L)

solubility

H2O: 100 mg/mL

storage temp.

room temp

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This Item
D6001D8906D8787
form

powder

form

powder

form

powder

form

powder or crystals

color

white to light yellow

color

white to off-white

color

off-white

color

white to off-white

useful pH range

6.0-8 (10 g/L)

useful pH range

6.0-8.0 (1% in water)

useful pH range

6.0-8 (10 g/L)

useful pH range

-

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

General description

Dextran sulfate is a sulfated polysaccharide, which is negatively charged. It is produced by the esterification of dextran with chlorosulphonic acid. Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli. It is a ribonuclease inhibitor. Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
  • for RNA sequential probing of targets (SPOTs) imaging(61)
  • as a component of 1% injection buffer(62)

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Customers Also Viewed

The Molecular Biology of Poliovirus (2012)
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Parisa Yousefpour et al.
International journal of nanomedicine, 6, 1487-1496 (2011-07-29)
This study deals with the preparation and investigation of a nanoscale delivery system for the anticancer drug doxorubicin (DOX) using its complexation with polyanionic carbohydrate dextran sulfate (DS). Dynamic light scattering, SEM, and zeta potential determination were used to characterize
Radiotherapy, Surgery, and Immunotherapy (2012)
Rheology of Industrial Polysaccharides: Theory and Applications (2012)

Protocols

Dextran Sulfate

Dextran sulfates are supplied as the sodium salt forms, making them soluble and stable in water. Dextran sulfate contains approximately 17% sulfur which is equivalent to approximately 2.3 sulfate groups per glucosyl residue.

Related Content

Dextran and Related Polysaccharides

Learn about C6H10O6 or dextran formation, classes and naming. Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, which have a linear backbone of α-linked d-glucopyranosyl repeating units.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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