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N7143

Sigma-Aldrich

Nigericin sodium salt

≥98% (TLC)

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Synonym(s):
Antibiotic K178, Antibiotic X464, Azalomycin M, Helexin C, Polyetherin A
Empirical Formula (Hill Notation):
C40H67NaO11
CAS Number:
Molecular Weight:
746.94
Beilstein/REAXYS Number:
3892398
MDL number:
PubChem Substance ID:
NACRES:
NA.77

biological source

Streptomyces hygroscopicus

Quality Level

assay

≥98% (TLC)

form

powder

antibiotic activity spectrum

Gram-positive bacteria

mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

[Na+].[H][C@@]1(CC[C@H](C)[C@@]([H])(O1)[C@@H](C)C([O-])=O)C[C@]2([H])C[C@@H](OC)[C@@H](C)[C@]3(O2)O[C@@](C)(C[C@H]3C)[C@@]4([H])CC[C@](C)(O4)[C@]5([H])O[C@]([H])(C[C@@H]5C)[C@@]6([H])O[C@@](O)(CO)[C@H](C)C[C@@H]6C

InChI

1S/C40H68O11.Na/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22(2)15-24(4)39(44,20-41)50-34;/h21-35,41,44H,11-20H2,1-10H3,(H,42,43);/q;+1/p-1/t21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35+,37-,38-,39-,40+;/m0./s1

InChI key

MOYOTUKECQMGHE-PDEFJWSRSA-M

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1 of 4

This Item
SML1779S6201S4526
vibrant-m

N7143

Nigericin sodium salt

vibrant-m

S6201

Salinomycin, Ready Made Solution

vibrant-m

S4526

Salinomycin

assay

≥98% (TLC)

assay

-

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

biological source

Streptomyces hygroscopicus

biological source

Streptomyces hygroscopicus

biological source

Streptomyces albus

biological source

Streptomyces albus

antibiotic activity spectrum

Gram-positive bacteria

antibiotic activity spectrum

Gram-positive bacteria

antibiotic activity spectrum

neoplastics

antibiotic activity spectrum

neoplastics

General description

Chemical structure: polyether

Biochem/physiol Actions

Polyether ionophore that disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K+> Rb+≥ Cs+>> Na+.

Other Notes

As ion-selective electrode - an efficient K+-carrier.

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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