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Merck
모든 사진(3)

주요 문서

C9755

Sigma-Aldrich

Cytidine 5′-diphosphate sodium salt hydrate

from yeast, ≥95%

동의어(들):

CDP sodium salt hydrate

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About This Item

실험식(Hill 표기법):
C9H15N3O11P2
Molecular Weight:
403.18
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:
NACRES:
NA.51

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생물학적 소스

yeast

Quality Level

분석

≥95%

양식

powder

저장 온도

−20°C

SMILES string

[Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(=O)OP(O)(O)=O)C(O)C2O

InChI

1S/C9H15N3O11P2.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18);;

InChI key

MAGSIBHRUIBONY-UHFFFAOYSA-N

관련 카테고리

일반 설명

Cytidine 5′-diphosphate (CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK).[1] CTP synthetase catalyzes the conversion of CTP to CDP intermediates like CDP-diacylglycerol, CDP-choline and CDP-ethanolamine for phospholipid biosynthesis.[2]

애플리케이션

Cytidine 5′-diphosphate sodium salt hydrate has been used:
  • as a substrate in nucleoside diphosphatase (NDPase) enzyme histochemistry assay of gold fish eye sections[3]
  • in ribonucleotide reductase assay
  • dCDP formation assay.[4]

생화학적/생리학적 작용

Cytidine 5′-diphosphate (CDP) is used as a substrate of nucleoside diphosphatase kinase[3] to produce CTP for supporting DNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yan Zhang et al.
Biochemistry, 50(25), 5615-5623 (2011-05-13)
Bacillus subtilis class Ib ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to deoxynucleotides, providing the building blocks for DNA replication and repair. It is composed of two proteins: α (NrdE) and β (NrdF). β contains the metallo-cofactor, essential for
Microglial cells in the retina of Carassius auratus: effects of optic nerve crush
Salvador-Silva M, et al.
The Journal of Comparative Neurology, 417(4), 431-447 (2000)
Ribonucleotide reductase requires subunit switching in hypoxia to maintain DNA replication
Foskolou IP, et al.
Molecular Cell, 66(2), 206-220 (2017)
Purine and pyrimidine nucleotide synthesis and metabolism
The Arabidopsis Book / American Society of Plant Biologists, 1 (2002)
CTP synthetase and its role in phospholipid synthesis in the yeast Saccharomyces cerevisiae
Chang YF and Carman GM
Progress in Lipid Research, 47(5), 333-339 (2008)

프로토콜

ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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