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T7004

Sigma-Aldrich

Thymidine 5′-monophosphate disodium salt hydrate

≥99%

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Synonym(s):
5′-Thymidylic acid disodium salt, TMP, dTMP
Empirical Formula (Hill Notation):
C10H13N2Na2O8P · xH2O
CAS Number:
Molecular Weight:
366.17 (anhydrous basis)
Beilstein/REAXYS Number:
4086927
EC Number:
MDL number:
PubChem Substance ID:

assay

≥99%

storage temp.

−20°C

SMILES string

O.[Na+].[Na+].CC1=CN([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)C(=O)NC1=O

InChI

1S/C10H15N2O8P.2Na.H2O/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t6-,7+,8+;;;/m0.../s1

InChI key

KCOPAVKVHIWPKB-SPSULGLQSA-L

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1 of 4

This Item
U6375D3876T4510
assay

≥99%

assay

≥99%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

Thymidine 5′-monophosphate de novo synthesis from deoxyuridine monophosphate (dUMP) is catalyzed by the enzyme thymidylate synthase.

Application

Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard for the quantification of metabolites from plasma and tumor interstitial fluid using liquid chromatography-mass spectrometry analysis (LC/MS). It has also been used as a single deoxy-mononucleotide to test its effect on the cell growth of human malignant intestinal CaCo-2 cells and normal rat intestinal cell line IEC-6 cells.
Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard solution.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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