D2625

Dansyl chloride

BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)

• 동의어(들): 5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl
• 실험식(Hill 표기법): C₁₂H₁₂ClNO₂S
• CAS Number: 605-65-2
• Molecular Weight: 269.75
• Beilstein: 2217205
• EC Number: 210-092-6
• MDL number: MFCD00003985
• UNSPSC 코드: 12352101
• PubChem Substance ID: 24893700
• NACRES: NA.26

속성

• 제품 라인: BioReagent
• Quality Level: 200
• 분석: ≥99% (HPLC)
• 양식: powder and chunks
• 색상: yellow to yellow-orange
• mp: 72-74 °C (lit.)
• solubility: acetone: 20 mg/mL
• 적합성: suitable for amino acid labeling
• 저장 온도: 2-8°C
• SMILES string: CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
• InChI: 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
• InChI key: XPDXVDYUQZHFPV-UHFFFAOYSA-N

설명

애플리케이션

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

Dansyl chloride has been used:

• as a fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase high performance liquid chromatography (HPLC)
• in the derivatization of plasma samples
• in the quantification of immobilized alkaline phosphatase

생화학적/생리학적 작용

Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins. Dansyl chloride is used for derivatization of free amino acids and amines in neural samples and biological fluids. It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H290,H314
• 예방조치 성명서: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges