추천 제품
무균
non-sterile
Quality Level
형태
lyophilized powder
라벨링 범위
~30 mol steroid per mol BSA
solubility
phosphate buffer: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
배송 상태
ambient
저장 온도
2-8°C
일반 설명
β-Estradiol 6-(O-carboxymethyl)oxime: BSA is an estradiol conjugate and is membrane-impermeable. BSA is linked to the estradiol at position 6 to form the β-estradiol 6-(O-carboxymethyl) oxime: BSA conjugate.
애플리케이션
β-Estradiol 6-(O-carboxymethyl)oxime: BSA has been used:
- to test its effect on the N-methyl-D-aspartate receptor (NMDAR) currents in female dorsal root ganglion (DRG) neurons
- to coat microplates for the detection of plasma 17β-Estradiol levels using indirect enzyme-linked immunosorbent assay (ELISA)
- to test its effect on MutL homolog 1 in colorectal cancer lines
생화학적/생리학적 작용
β-Estradiol 6-(O-carboxymethyl)oxime: BSA mimics estrogen and favors amyloid precursor protein α (sAPPα) secretion in vitro studies with primary rat cortical neurons. It also stimulates mitogen-activated protein kinase (MAPK) activity in human umbilical vein endothelial cells
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Adrián Tintos et al.
Ecotoxicology and environmental safety, 66(2), 139-147 (2006-02-10)
To assess the effects of naphthalene on liver intermediary metabolism and plasma steroid hormones, immature female rainbow trout (Oncorhynchus mykiss), in a first experiment, were intraperitoneally injected (2 microLg(-1)) with vegetable oil alone (control) or containing naphthalene (10 and 50
Sex-dependent differences in the activity and modulation of N-methyl-d-aspartic acid receptors in rat dorsal root ganglia neurons.
McRoberts, et al.
Neuroscience, 148, 1015-1020 (2018)
Sun Zhang et al.
Acta pharmacologica Sinica, 26(2), 171-176 (2005-01-25)
To investigate the mechanism of the action of estrogen, which stimulates the release of secreted amyloid precursor protein alpha (sAPP(alpha)) and decreases the generation of amyloid-beta protein (A(beta)), a dominant component in senile plaques in the brains of Alzheimer's disease
K S Russell et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(11), 5930-5935 (2000-05-24)
Estrogen induces both rapid and delayed effects on the cardiovascular system. The early effects take place within minutes (e.g., changes in vasomotor tone) and are mediated through rapid intracellular signaling pathways; whereas the delayed effects (e.g., remodeling or lipid alterations)
Claudio R F Marinho et al.
PloS one, 4(5), e5630-e5630 (2009-05-23)
Pregnancy-associated malaria (PAM) is associated with placenta pathology and poor pregnancy outcome but the mechanisms that control the malaria parasite expansion in pregnancy are still poorly understood and not amenable for study in human subjects. Here, we used a set
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