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Merck
모든 사진(1)

주요 문서

H8664

Sigma-Aldrich

Steviol hydrate

≥98% (HPLC), powder

동의어(들):

(4α)-13-Hydroxykaur-16-en-18-oic acid hydrate

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About This Item

실험식(Hill 표기법):
C20H30O3 · xH2O
CAS Number:
Molecular Weight:
318.45 (anhydrous basis)
MDL number:
UNSPSC 코드:
12161501
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

양식

powder

색상

white to tan

solubility

DMSO: >10 mg/mL

저장 온도

2-8°C

SMILES string

O.C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](O)(CC[C@@H]23)C4)C(O)=O

InChI

1S/C20H30O3.H2O/c1-13-11-19-9-5-14-17(2,7-4-8-18(14,3)16(21)22)15(19)6-10-20(13,23)12-19;/h14-15,23H,1,4-12H2,2-3H3,(H,21,22);1H2/t14-,15-,17+,18+,19+,20-;/m0./s1

InChI key

SGPAFVVDOPSBEU-CRRYNOPCSA-N

생화학적/생리학적 작용

Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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이미 열람한 고객

Slide 1 of 1

1 of 1

Stevioside primary reference standard

05420590

Stevioside

Midori Takasaki et al.
Bioorganic & medicinal chemistry, 17(2), 600-605 (2009-01-10)
In a search for potential cancer chemopreventive agents from natural resources, stevioside (1), a sweetener, and six related compounds, including two aglycones steviol (6) and isosteviol (7), were screened in an in vitro assay for inhibitory effects on Epstein-Barr virus
[Steviol glycosides as sweetener in diabetes?].
K Tuttas et al.
Deutsche medizinische Wochenschrift (1946), 137(15), 806-806 (2012-04-12)
Motohiko Ukiya et al.
Chemistry & biodiversity, 10(2), 177-188 (2013-02-19)
Seventeen steviol derivatives, i.e., 2-18, and 19 isosteviol derivatives, i.e., 19-37, were prepared from a diterpenoid glycoside, stevioside (1). Upon evaluation of the cytotoxic activities of these compounds against leukemia (HL60), lung (A549), stomach (AZ521), and breast (SK-BR-3) cancer cell
Amal A A Mohamed et al.
Journal of plant physiology, 168(10), 1136-1141 (2011-04-12)
A short-term experiment was designed to measure the transcript levels of downstream genes contributing to the biosynthesis of steviol glycosides. Stevia rebaudiana plants were subjected to long- and short-day conditions for different time intervals. Samples from both lower and upper
Valerio Pieri et al.
Journal of agricultural and food chemistry, 59(9), 4378-4384 (2011-03-23)
The use of (1)H NMR spectroscopy for the characterization of Stevia rebaudiana extracts is presented. The developed method allows qualitative and quantitative determination of the major steviol glycosides in purified extracts and fractions obtained from various stages of the purification

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