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Merck
모든 사진(5)

주요 문서

L9125

Sigma-Aldrich

L-Leucine-p-nitroanilide

leucine aminopeptidase substrate, chromogenic, ≥98% (TLC), powder

동의어(들):

L-Leucine-4-nitroanilide

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About This Item

실험식(Hill 표기법):
C12H17N3O3
CAS Number:
Molecular Weight:
251.28
Beilstein:
2218433
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32

제품명

L-Leucine-p-nitroanilide, leucine aminopeptidase substrate

분석

≥98% (TLC)

양식

powder

solubility

ethanol: 50 mg/mL

저장 온도

2-8°C

SMILES string

CC(C)C[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1

InChI key

AXZJHDNQDSVIDR-NSHDSACASA-N

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애플리케이션

L-Leucine-p-nitroanilide has been used as substrate
  • for the determination of intestinal leucine aminopeptidase activity of juvenile rainbow trout (Oncorhynchus mykiss)
  • in insulin-regulated aminopeptidase inhibition assay
  • for determining exopeptidase activity

기질

Substrate for the colorimetric determination of leucine aminopeptidase.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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시험 성적서(COA)

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이미 열람한 고객

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Natasa Bozić et al.
Electrophoresis, 26(12), 2476-2480 (2005-05-28)
A general method for detecting leucyl aminopeptidase activity after native polyacrylamide gel electrophoresis (PAGE) in situ is described. The method is based on diazotization of p-nitroaniline, liberated in the polyacrylamide gel by leucyl aminopeptidase action on leucine-p-nitroanilide (LpNA) and subsequent
Pablo Emiliano Cantón et al.
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C Toma et al.
Infection and immunity, 64(11), 4495-4500 (1996-11-01)
The structural gene for the Vibrio cholerae leucine aminopeptidase (lap) was cloned and sequenced. The cloned DNA fragment contained a 1,503-bp open reading frame potentially encoding a 501-amino-acid polypeptide with a calculated molecular mass of 54,442 Da. The deduced amino
Reishi Toshiyama et al.
Oncogene, 38(2), 244-260 (2018-08-10)
Previous studies highlighted that aminopeptidase N (APN)/CD13 acts as a scavenger in the survival of hepatocellular carcinoma (HCC) stem cells by reducing reactive oxygen species (ROS) levels. Hence, it has been proposed that APN/CD13 inhibition can increase cellular ROS levels

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