SML1238

Ertapenem sodium

≥90% (HPLC), powder, carbopenem antibiotic

• 동의어(들): (4R,5S,6S)-3-[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium, ZD-443 sodium
• 실험식(Hill 표기법): C₂₂H₂₄N₃O₇S · Na
• CAS Number: 153773-82-1
• Molecular Weight: 497.50
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• 제품명: Ertapenem sodium, ≥90% (HPLC)
• Quality Level: 100
• 분석: ≥90% (HPLC)
• 양식: powder
• 저장 조건: desiccated; protect from light
• 색상: white to beige
• solubility: H₂O: 20 mg/mL, clear
• 배송 상태: wet ice
• 저장 온도: −70°C
• SMILES string: [Na+].S([C@@H]3CN[C@@H](C3)C(=O)Nc4cc(ccc4)C(=O)[O-])C1=C(N2[C@H]([C@H]1C)[C@H](C2=O)[C@H](O)C)C(=O)O
• InChI: 1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1
• InChI key: ZXNAQFZBWUNWJM-HRXMHBOMSA-M

설명

애플리케이션

Ertapenem sodium has been used as a carbapenem in the NitroSpeed-Carba NP test in minimum inhibitory concentration (MIC) testing for differentiation of carbapenemases in Enterobacterales and Pseudomonas aeruginosa. It has also been used as an antibiotic to study its effects on the survival of septic mice.

생화학적/생리학적 작용

Broad spectrum carbopenem antibiotic

Ertapenem is a broad spectrum carbopenem antibiotic. Ertapenem is active against both gram-positive and gram-negative bacteria. Ertapenem shows an extended duration of action in vivo due to its reversible binding to serum protein.

Ertapenem sodium exhibits its activity against several aerobic and anaerobic microorganisms and is more resistant to β-lactamase enzymes. It has been studied in the treatment of several infectious diseases.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable