SML2461
LM22B-10
≥98% (HPLC)
동의어(들):
2,2′,2′′,2′′′-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis[ethanol], 2,2′,2′,2′′′-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C27H33ClN2O4
CAS Number:
Molecular Weight:
485.01
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
![[D-Lys6]-LH-RH](/deepweb/assets/sigmaaldrich/product/images/327/956/6215aa07-cc81-40f5-97b7-5b2283044678/640/6215aa07-cc81-40f5-97b7-5b2283044678.jpg)
분석
≥98% (HPLC)
양식
powder
색상
faint blue to green
solubility
DMSO: 2 mg/mL, clear
저장 온도
−20°C
SMILES string
ClC1=CC=C(C(C2=CC=C(N(CCO)CCO)C=C2)C3=CC=C(N(CCO)CCO)C=C3)C=C1
InChI key
QCXQLSGBOUUVNH-UHFFFAOYSA-N
생화학적/생리학적 작용
LM22B-10 is a brain penetrant, potent and selective TrkB and TrkC neurotrophin receptors agonist that improves cell survival and potently accelerated neurite outgrowth. LM22B-10 inhibits binding of BDNF to TrkB-expressing cells and NT-3 to TrkC-expressing cells.
brain penetrant, potent and selective TrkB and TrkC agonist
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Tao Yang et al.
Neuropharmacology, 110(Pt A), 343-361 (2016-06-24)
Neurotrophin (NT) receptors are coupled to numerous signaling networks that play critical roles in neuronal survival and plasticity. Several non-peptide small molecule ligands have recently been reported that bind to and activate specific tropomyosin-receptor kinase (Trk) NT receptors, stimulate their
Tao Zhang et al.
Asian Pacific journal of tropical medicine, 10(12), 1172-1176 (2017-12-23)
To study the influence of glycyrrhetinic acid (GA) on bronchial asthma (BA) smooth muscle proliferation and apoptosis as well as inflammatory factor expression and its molecular mechanism. Male SD guinea pigs were selected and made into asthma models, bronchial asthma
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