추천 제품
생물학적 소스
human
재조합
expressed in E. coli
분석
≥95% (SDS-PAGE)
형태
liquid
분자량
41.5 kDa (384 aa, 1-364 aa + His Tag)
포장
pkg of 100 μg
농도
1 mg/mL
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−70°C
유전자 정보
human ... ALDOA(226)
일반 설명
Aldolase A (ALDOA) is a ubiquitous glycolytic enzyme expressed in developing embryos and in adult muscles. The gene encoding it is localized on human chromosome 16p11.2. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
생화학적/생리학적 작용
In glycolysis, aldolase A (ALDOA) catalyzes the reversible reaction of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate and dihydroxyacetone phosphate. It is involved in a wide range of cellular functions such as maintenance of striated muscle contraction, cell shape and mobility, actin filament organization and ATP biosynthetic process. High expression level of ALDOA is reported in various forms of malignant cancers, including human lung squamous, renal cell and hepatocellular carcinomas. ALDOA deficiency causes myopathy and hemolytic anemia.
물리적 형태
1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl and 10% glycerol.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Association and Mutation Analyses of 16p11.2 Autism Candidate Genes
Ravinesh A
PLoS ONE (2009)
Two cases of red cell aldolase deficiency associated with hereditary hemolytic anemia in a Japanese family.
Miwa S
American Journal of Hematology, 11(4) (1981)
Comparative proteomics analysis of gastric cancer stem cells.
Morisaki T
PLoS ONE, 9(14) (2014)
Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation.
Kishi H
Proceedings of the National Academy of Sciences of the USA, 84(23) (1987)
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration.
Sha Du
PLoS ONE, 9(9) (2014)
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.