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일반 설명
The cardiac troponin T gene (TNNT2) is located on human chromosome 1 and spans around 17kb. It codes for a 288-amino-acid peptide of 36−39kDa.[1]
애플리케이션
Troponin T from human heart has been used in competitive enzyme-linked immunosorbent assay (ELISA) for the quantification of troponin T (TnT).[2]
생화학적/생리학적 작용
The tropomyosin-binding subunit of troponin. The cardiac troponin T gene (TNNT2) helps to connect the troponin complex to α-tropomyosin, thereby participates in the modulation of contractile function.[1]
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Inherited cardiomyopathies
Emery and Rimoin's Principles and Practice of Medical Genetics, 1-38 (2013)
A skeletal muscle troponin T specific ELISA based on the use of an antibody against the soluble troponin T (16-31) fragment
Tsitsilonis O E, et al.
Journal of Immunological Methods, 268(2), 141-148 (2002)
Nikita Sitkov et al.
Micromachines, 12(6) (2021-07-03)
The problems of chronic or noncommunicable diseases (NCD) that now kill around 40 million people each year require multiparametric combinatorial diagnostics for the selection of effective treatment tactics. This could be implemented using the biosensor principle based on peptide aptamers
문서
Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin
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