Copper-promoted sulfenylation of sp2 C-H bonds.

Copper-promoted sulfenylation of sp2 C-H bonds.

Journal of the American Chemical Society (2012-10-30)

Ly Dieu Tran, Ilya Popov, Olafs Daugulis

PMID23102009

초록

An auxiliary-assisted, copper catalyzed or promoted sulfenylation of benzoic acid derivative β-C-H bonds and benzylamine derivative γ-C-H bonds has been developed. The method employs disulfide reagents, copper(II) acetate, and DMSO solvent at 90-130 °C. Application of this methodology to the direct trifluoromethylsulfenylation of C-H bonds was demonstrated.

MATERIALS

제품 번호

브랜드

제품 설명

73983

Supelco

Mettler-Toledo Calibration substance ME 18555, Benzoic acid, analytical standard, (for the calibration of the melting point system), traceable to primary standards (LGC)

W213128

Sigma-Aldrich

Benzoic acid, natural, ≥99.5%, FCC, FG

290009

Sigma-Aldrich

Potassium benzoate, ReagentPlus^®, 99%

W213101

Sigma-Aldrich

Benzoic acid, ≥99.5%, FCC, FG

33047

Sigma-Aldrich

Benzoic acid, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.9% (alkalimetric)